9-(2-Carboxyphenyl)-2,7-dimethyl-3,6-bis(ethylamino)xanthylium
CAS: 25152-49-2
Ref. TR-C178520
| 100mg | 158.00 € | ||
| 250mg | 283.00 € | ||
| 500mg | 468.00 € |
Product Information
- Rhodamine 19
- Rhodamine 19 Zwitterion
- Rhodamine 575
- o-[6-(Ethylamino)-3-(ethylimino)-2,7-dimethyl-3H-xanthen-9-yl]-benzoic Acid
- 9-(2-Carboxyphenyl)-3,6-bis(ethylamino)-2,7-dimethylxanthylium Inner Salt
Applications 9-(2-Carboxyphenyl)-2,7-dimethyl-3,6-bis(ethylamino)xanthylium is an intermediate in the synthesis of SkQR1 (S555050), a mitochondria-targeted plastoquinone antioxidant that exhibits neuroprotective effect. Potent Mitochondrial Targeted antioxidant protecting against the anti-cancer treatment related to oxidative stress (1). Depicted positive effects on rat memory. (2)SkQRl is the substrate of multidrug resistance pump P-glycoproten (Pgp 170) and selectively protects Pgp 170-negative cells against oxidative stress (3)
References Fetisova EK, et al. 2010. FEBS Lett. Feb 5;584(3):562-6Stelmashook EV, 2015. Biochemistry (Mosc). May;80(5):592-5 Fetisova EK, et al. 2015. Radiat Res. Jan;183(1):64-71
Chemical properties
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