(Z)-7-(((2R)-2-Carboxy-2-((4-oxopentan-2-yl)amino)ethyl)thio)-2-((S)-2,2-dimethylcyclopropanecarboxa

Ref. TR-C178930

Product Information

• Name: (Z)-7-(((2R)-2-Carboxy-2-((4-oxopentan-2-yl)amino)ethyl)thio)-2-((S)-2,2-dimethylcyclopropanecarboxa
• Synonyms: Cilastatin Impurity B

Description

Applications (Z)-7-(((2R)-2-Carboxy-2-((4-oxopentan-2-yl)amino)ethyl)thio)-2-((S)-2,2-dimethylcyclopropanecarboxamido)hept-2-enoic Acid is an impurity of Cilastatin (C441100), prevents renal metabolism of penem and carbapenem antibiotics by specific and reversible dehydropeptidase I inhibition. Antibacterial adjunct.
References Finlay, K.R., et al.: Invest. Ophthalmol. Visual Sci., 24, 1147 (1983), Norrby, S.R., et al.: Antimicrob. Agents Chemother., 23, 300 (1983), Washburn, D.E., et al.: J. Antimicrob. Chemother., 12, 39 (1983),

• Brand: TRC

Chemical properties

• Molecular weight: 442.57
• Formula: C₂₁H₃₄N₂O₆S
• Purity: >90%
• Color/Form: Neat
• InChI: InChI=1S/C21H34N2O6S/c1-13(10-14(2)24)22-17(20(28)29)12-30-9-7-5-6-8-16(19(26)27)23-18(25)15-11-21(15,3)4/h8,13,15,17,22H,5-7,9-12H2,1-4H3,(H,23,25)(H,26,27)(H,28,29)/b16-8-/t13?,15-,17+/m0/s1
• InChI key: InChIKey=BUNBOTXVYUHQBA-RLDYRFIWSA-N
• SMILES: CC(=O)CC(C)N[C@H](CSCCCC/C=C(\NC(=O)[C@@H]1CC1(C)C)C(=O)O)C(=O)O