Estimated delivery in United States, on Friday 17 Jan 2025
Product Information
Name:
4-Carboxy Nevirapine
Controlled Product
Synonyms:
- 11-Cyclopropyl-6,11-dihydro-6-oxo-5H-dipyrido[3,2-b:2',3'-e][1,4]diazepine-4-carboxylic Acid
Description:
Stability Hygroscopic
Applications 4-Carboxy Nevirapine is a metabolite of Nevirapine (N391275); a potent (IC50=84nM) and selective non-nucleoside inhibitor of HIV-1 reverse transcriptase. Also antiviral.
References Hargrave, K.D., et al.: J. Med. Chem., 34, 2231 (1991); Cheeseman, S.H., et al.: Antimicrob. Agents Chemother., 37, 178 (1993); Guay, L.A., et al.: Lancet, 354, 795 (1999); Riska, P., et al.: Drug Metab. Dispos., 27, 895 (1999)
Notice:
Our products are intended for lab use only. For any other use, please contact us.
Brand:
TRC
Long term storage:
Notes:
Chemical properties
Molecular weight:
296.28
Formula:
C15H12N4O3
Color/Form:
Neat
InChI:
InChI=1S/C15H12N4O3/c20-14-10-2-1-6-16-12(10)19(8-3-4-8)13-11(18-14)9(15(21)22)5-7-17-13/h1-2,5-8H,3-4H2,(H,18,20)(H,21,22)
InChI key:
InChIKey=WDXCMIDQWGYHIN-UHFFFAOYSA-N
SMILES:
O=C1Nc2c(C(=O)O)ccnc2N(C2CC2)c2ncccc21
MDL:
Melting point:
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EINECS:
Merck:
HS code:
Technical inquiry about: TR-C181050 4-Carboxy Nevirapine
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