Estimated delivery in United States, on Tuesday 28 May 2024
Product Information
Name:
CH5424802
Synonyms:
- 9-Ethyl-6,11-dihydro-6,6-dimethyl-8-[4-(4-morpholinyl)-1-piperidinyl]-11-oxo-5H-benzocarbazole-3-carbonitrile
- Alectinib
- 5H-Benzo[b]carbazole-3-carbonitrile, 9-ethyl-6,11-dihydro-6,6-dimethyl-8-[4-(4-morpholinyl)-1-piperidinyl]-11-oxo-
- 9-Ethyl-6,11-dihydro-6,6-dimethyl-8-[4-(4-morpholinyl)-1-piperidinyl]-11-oxo-5H-benzo[b]carbazole-3-carbonitrile
- Af 802
- Alecensa free base
- Ch 5424802
- Ch 542480210
- Rg 7853
- Rg7853
- See more synonyms
CAS:
Description:
Applications CH5424802 is a highly selective and potent anaplastic lymphoma kinase (ALK) inhibitor capable of blocking the resistant gatekeeper mutant, which results in reduced cell growth. CH5424802 have been clinically evaluated for the treatment of patients with ALK-driven tumors. Potent ALK inhibitor
References Sakamoto, H., et al.: Cancer Cell., 19, 679 (2011); Kinoshita, K., et al.: Bio-org. Medn., 20, 1271 (2012);
Brand:
TRC
Long term storage:
Notes:
Chemical properties
Molecular weight:
482.62
Formula:
C30H34N4O2
Color/Form:
Neat
SMILES:
CCc1cc2c(cc1N1CCC(N3CCOCC3)CC1)C(C)(C)c1[nH]c3cc(C#N)ccc3c1C2=O
MDL:
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EINECS:
Merck:
HS code:
Technical inquiry about: TR-C183360 CH5424802
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