Carfilzomib (2R,4R)-Diol
Ref. TR-C183525
| 10mg | 3,433.00 € | ||
| 500µg | 252.00 € | ||
| 2500µg | 1,065.00 € |
Estimated delivery in United States, on Friday 13 Dec 2024
Product Information
Name:
Carfilzomib (2R,4R)-Diol
Controlled Product
Synonyms:
- (S)-N-((S)-1-(((2R,4R)-1,2-Dihydroxy-2,6-dimethyl-3-oxoheptan-4-yl)amino)-1-oxo-3-phenylpropan-2-yl)-4-methyl-2-((S)-2-(2-morpholinoacetamido)-4-phenylbutanamido)pentanamide
Description:
Applications Carfilzomib (2R,4R)-Diol is a derivative of Carflizomib (C183460), a second-generation proteasome inhibitor that is used as a treatment in relapsed and refractory multiple myeloma.
References Fostier, K., et al.: Oncotargets. Therap., 5, 237 (2012); Geurink, P.P., et al.: J. Med. Chem., 56, 1262 (2013); McCormack, P.L., et al.: Drugs., 72, 2023 (2012);
Notice:
Our products are intended for lab use only. For any other use, please contact us.
Brand:
TRC
Long term storage:
Notes:
Chemical properties
Molecular weight:
737.93
Formula:
C40H59N5O8
Color/Form:
Neat
InChI:
InChI=1S/C40H59N5O8/c1-27(2)22-32(36(48)40(5,52)26-46)42-39(51)34(24-30-14-10-7-11-15-30)44-38(50)33(23-28(3)4)43-37(49)31(17-16-29-12-8-6-9-13-29)41-35(47)25-45-18-20-53-21-19-45/h6-15,27-28,31-34,46,52H,16-26H2,1-5H3,(H,41,47)(H,42,51)(H,43,49)(H,44,50)/t31-,32+,33-,34-,40+/m0/s1
InChI key:
InChIKey=ABPYUKBBMCBILQ-XOLRBGIHSA-N
SMILES:
CC(C)C[C@H](NC(=O)[C@H](CCc1ccccc1)NC(=O)CN1CCOCC1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@H](CC(C)C)C(=O)[C@](C)(O)CO
MDL:
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Technical inquiry about: TR-C183525 Carfilzomib (2R,4R)-Diol
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