Carmustine

CAS: 154-93-8

Ref. TR-C183875

Product Information

• Name: Carmustine
• Synonyms: 1,3-bis(2-chloroethyl)-1-nitrosourea, 1,3-Bis(2-Chloroethyl)-1-Nitroso-Urea, 1,3-Bis(2-chlorethyl)-1-nitrosourea, 1,3-Bis(2-chloroethyl)-1-nitrosourea, 1,3-Bis(2-chloroethyl)nitrosourea, 1,3-Bis(β-chloroethyl)-1-nitrosourea, Bcnu, Becenum, Becenun, BiCNU, Carmubris, Carmustin, Carmustina, Dti 015, Fda 0345, Gliadel, Gliadel Wafer, N,N'-Bis(2-chloroethyl)-N-nitrosourea, Nitrumon, Nsc 409962, Sk 27702, Sri 1720, Urea, 1,3-bis(2-chloroethyl)-1-nitroso-, Urea, N,N'-bis(2-chloroethyl)-N'-nitroso-

Description

Stability Temperature Sensitive
Applications An alkylating and carbamoylating nitrosourea compound. It interacts with DNA, RNA and proteins causing DNA interstrand cross linking which is cytotoxic and leads to apoptotic cell death.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Stahl, et al.: Chem. Res. Toxicol., 5, 106 (1992), Kokkinakis, D.M., et al.: Clin. Cancer Res., 5(11), 3676 (1999), Hickman, M.J., et al.: Proc. Natl. Acad. Sci. USA, 96(19), 10764 (1999),

• Brand: TRC

Chemical properties

• Molecular weight: 214.05
• Formula: C₅H₉Cl₂N₃O₂
• Color/Form: Light Yellow To Light Orange Colour
• InChI: InChI=1S/C5H9Cl2N3O2/c6-1-3-8-5(11)10(9-12)4-2-7/h1-4H2,(H,8,11)
• InChI key: InChIKey=DLGOEMSEDOSKAD-UHFFFAOYSA-N
• SMILES: O=NN(CCCl)C(=O)NCCCl