N-Cbz-D-methionine

CAS: 28862-80-8

Ref. TR-C227740

Product Information

• Name: N-Cbz-D-methionine
• Synonyms: N-[(Phenylmethoxy)carbonyl]-D-methionine, (2R)-4-Methylsulfanyl-2-(phenylmethoxycarbonylamino)butanoic acid, (R)-2-(Benzyloxycarbonylamino)-4-(methylthio)butanoic acid, <span class="text-smallcaps">D</span>-(Carbobenzyloxy)methionine, <span class="text-smallcaps">D</span>-Methionine, N-[(phenylmethoxy)carbonyl]-, CBZ-<span class="text-smallcaps">D</span>-Methionine, Cbz-D-methionine, Methionine, N-carboxy-, N-benzyl ester, <span class="text-smallcaps">D</span>-, N-(Benzyloxycarbonyl)-<span class="text-smallcaps">D</span>-methionine, N-Benzyloxycarbonyl-D-methionine, N-Carbobenzoxy-D-methionine, N-Carbobenzyloxy-<span class="text-smallcaps">D</span>-methionine, N-[(Phenylmethoxy)carbonyl]-<span class="text-smallcaps">D</span>-methionine, z-D-Met

Description

Applications N-Cbz-D-methionine is an N-Cbz-protected form of D-Methionine (M260550). D-Methionine is an isomer of L-Methionine (M260440), and is known to be a cytoprotectant against Cisplatin (C499500), an anticancer agent. D-Methionine is also used to prevent noise- and drug-induced hearing loss, as well as hair loss (all of which may also be caused by Cisplatin or aminoglycosides).
References Campbell, K., et al.: Hear. Res., 92, 103 (2007); Cloven, N., et al.: Antican. Res., 20.6B, 4205 (1999); Vuyyuri, S., et al.: Clin. Cancer Res., 14, 2161 (2008)

• Brand: TRC

Chemical properties

• Molecular weight: 283.34
• Formula: C₁₃H₁₇NO₄S
• Color/Form: Neat
• InChI: InChI=1S/C13H17NO4S/c1-19-8-7-11(12(15)16)14-13(17)18-9-10-5-3-2-4-6-10/h2-6,11H,7-9H2,1H3,(H,14,17)(H,15,16)/t11-/m1/s1