Product Information
Name:CCT036477
Controlled Product
Synonyms:
- α-(4-Chlorophenyl)-2-methyl-N-2-pyridinyl-1H-indole-3-methanamine
Brand:TRC
Description:Applications CCT036477 is an inhibitor of Wnt signaling. Studies show that CCT036477 does not alter β-catenin levels but blocks transcription at the β-catenin level. CCT036477 inhibited growth in several cancer cell lines and showed clear activity in vivo, blocking development of Zebrafish and Xenopus embryos and expression of Wnt target genes.References Ewan, K. et al.: Cancer Res., 14, 5963 (2010);
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:347.84
Formula:C21H18ClN3
Color/Form:Neat
InChI:InChI=1S/C21H18ClN3/c1-14-20(17-6-2-3-7-18(17)24-14)21(15-9-11-16(22)12-10-15)25-19-8-4-5-13-23-19/h2-13,21,24H,1H3,(H,23,25)
InChI key:InChIKey=IFOHRIXRQPOHQZ-UHFFFAOYSA-N
SMILES:Cc1[nH]c2ccccc2c1C(Nc1ccccn1)c1ccc(Cl)cc1
Technical inquiry about: CCT036477
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