Cephalothin Sodium

CAS: 58-71-9

Ref. TR-C261155

Product Information

• Name: Cephalothin Sodium
• Synonyms: Cefalotin sodium, Sodium (6R,7R)-3-[(acetyloxy)methyl]-8-oxo-7-[(thiophen-2-ylacetyl)amino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate, 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 3-[(acetyloxy)methyl]-8-oxo-7-[[2-(2-thienyl)acetyl]amino]-, sodium salt (1:1), (6R,7R)-, 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 3-(hydroxymethyl)-8-oxo-7-[2-(2-thienyl)acetamido]-, acetate (ester), monosodium salt (8CI), 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 3-[(acetyloxy)methyl]-8-oxo-7-[(2-thienylacetyl)amino]-, monosodium salt, (6R,7R)- (9CI), 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 3-[(acetyloxy)methyl]-8-oxo-7-[(2-thienylacetyl)amino]-, monosodium salt, (6R-trans)-, 38253, Averon 1, Cefalothin sodium, Cefalothine sodium, Cemastin, Cephalothin sodium salt, Cephation, Ceporacin, Cepovenin, Coaxin, Keflin, Lilly 38253, Lospoven, Microtin, Seffin, Sodium (thienylacetamido)cephalosporanate, Sodium 3-acetoxymethyl-7ß-(2-thienylacetamido)ceph-3-em-4-carboxylate, Sodium 7-(2-thienylacetamido)-3-acetoxymethyl-3-cephem-4-carboxylate, Sodium 7-[2-(2-thienyl)acetamido]cephalosporanate, Sodium cefalotin, Sodium cephalothin, Sodium cephalotin, Synclotin, Toricelocin, 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 3-(hydroxymethyl)-8-oxo-7-[2-(2-thienyl)acetamido]-, acetate (ester), monosodium salt, 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 3-[(acetyloxy)methyl]-8-oxo-7-[(2-thienylacetyl)amino]-, monosodium salt, (6R,7R)-, 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 3-[(acetyloxy)methyl]-8-oxo-7-[(2-thienylacetyl)amino]-, monosodium salt, (6R-trans)-, 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 3-[(acetyloxy)methyl]-8-oxo-7-[[2-(2-thienyl)acetyl]amino]-, sodium salt (1:1), (6R,7R)-, 5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 3-[(acetyloxy)methyl]-8-oxo-7-[[2-(2-thienyl)acetyl]amino]-, sodium salt, (6R,7R)- (1:1), Cefalothin Sodium, Cefalotin Sodium, Cephalothin Sodium Cell Culture Tested, Cephalothin Sodium Crystalline, Cephalotin Sodium, Sodium 3-acetoxymethyl-7β-(2-thienylacetamido)ceph-3-em-4-carboxylate, Sodium Cephalothin

Description

Stability Hygroscopic
Applications Sodium salt of Cephalothin (C261150), a first generation cephalosporin antibiotic with a wide range antibacterial activity. It is effective against gram-positive and gram-negative bacteria, and has been tested in respiratory disease and neuromuscular junction studies.
References Shibata, K., et al.: J. Antibiot., 50, 135 (1997); Farra, A., et al.: Int. J. Antimicrob. Agents., 31, 427 (2008); Pichardo, C., et al.: Eur. J. Clin. Microbiol. Infect. Dis., 30, 289 (2011);

• Brand: TRC

Chemical properties

• Molecular weight: 418.42
• Formula: C₁₆H₁₅N₂O₆S₂·Na
• Color/Form: White
• InChI: +1/p-1/t12-,15-, /q, InChI=1S/C16H16N2O6S2.Na/c1-8(19)24-6-9-7-26-15-12(14(21)18(15)13(9)16(22)23)17-11(20)5-10-3-2-4-25-10, /m1./s1, /h2-4,12,15H,5-7H2,1H3,(H,17,20)(H,22,23)
• InChI key: InChIKey=VUFGUVLLDPOSBC-XRZFDKQNSA-M
• SMILES: CC(=O)OCC1=C(C(=O)O[Na])N2C(=O)[C@@H](NC(=O)Cc3cccs3)[C@H]2SC1