C3 Ceramide

CAS: 362678-52-2

Ref. TR-C262520

Product Information

• Name: C3 Ceramide
• Synonyms: N-[(1S,2R,3E)-2-hydroxy-1-(hydroxymethyl)-3-heptadecenyl]propanamide, N-[(1S,2R,3E)-2-hydroxy-1-(hydroxymethyl)-3-heptadecen-1-yl]propanamide

Description

Applications C3 Ceramide is a biologically active, cell permeable, but nonphysiologic ceramide analog. C3 Ceramide was found to exhibit antitumor activities by inducing differentiation of human HL-60 leukemia cells. C3 Ceramide is considered a potential differentiation-inducing therapy for the treatment of cancer including acute myeloid leukemia.
References Kim, D.S., et al.: Life. Sci., 81, 1638 (2007); Park, J., et al.: Bioorg. Med. Chem., 13, 2589 (2005); Chang, Y.T.,et al.: J. Am. Chem. Soc., 124, 1856 (2002);

• Brand: TRC

Chemical properties

• Molecular weight: 355.56
• Formula: C₂₁H₄₁NO₃
• Color/Form: Neat
• InChI: InChI=1S/C21H41NO3/c1-3-5-6-7-8-9-10-11-12-13-14-15-16-17-20(24)19(18-23)22-21(25)4-2/h16-17,19-20,23-24H,3-15,18H2,1-2H3,(H,22,25)/b17-16+/t19-,20+/m0/s1