Product Information
Name:Chebulinic Acid
Synonyms:
- β-D-Glucopyranose
- 1,3,6-tris(3,4,5-trihydroxybenzoate)
- cyclic 2→2:4→1-ester with (2S)-[(3R,4S)-5-carboxy-3,4-dihydro-3,7,8-trihydroxy-2-oxo-2H-1-benzopyran-4-yl]butanedioic acid
- 7,11-Methanopyrano[4,3,2-kl][2,5,8]benzotrioxacyclotridecin
- β-D-glucopyranose deriv.
- Eutannin
- NSC 69862
Brand:TRC
Description:
Applications Chebulinic Acid has been shown to prevent epithelial mesenchymal transition in retinal pigment epithelial cells through inhibition of SMAD-3 phosphorylation. This prevents retinal detachment in the process of proliferative vitreoretinopathy.
References Sivasankar, S. et al.: PLoS One., 10, e0120512 (2015);
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:956.68
Formula:C41H32O27
Color/Form:Neat
InChI:InChI=1S/C41H32O27/c42-15-1-10(2-16(43)26(15)51)35(56)62-9-22-31-33(66-36(57)11-3-17(44)27(52)18(45)4-11)34(41(63-22)68-37(58)12-5-19(46)28(53)20(47)6-12)67-38(59)13-7-21(48)29(54)32-25(13)24(30(55)40(61)65-32)14(8-23(49)50)39(60)64-31/h1-7,14,22,24,30-31,33-34,41-48,51-55H,8-9H2,(H,49,50)/t14-,22+,24-,30+,31+,33-,34+,41-/m0/s1
InChI key:InChIKey=YIJUMWSAXPLYOX-HXUWFJFHSA-N
SMILES:COc1cc(O)cc([C@@H](NC(=O)c2cccc(Cl)c2)C(=O)c2ccc(O)cc2O)c1
Technical inquiry about: Chebulinic Acid
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