Chloramphenicol Palmitate

CAS: 530-43-8

Ref. TR-C325035

Product Information

• Name: Chloramphenicol Palmitate
• Synonyms: (2R,3R)-2-[(dichloroacetyl)amino]-3-hydroxy-3-(4-nitrophenyl)propyl hexadecanoate, 2-[(Dichloroacetyl)Amino]-3-Hydroxy-3-(4-Nitrophenyl)Propyl Hexadecanoate, <span class="text-smallcaps">D</span>-(-)-Chloramphenicol palmitate, Acetamide, 2,2-dichloro-N-[β-hydroxy-α-(hydroxymethyl)-p-nitrophenethyl]-, α-palmitate, <span class="text-smallcaps">D</span>-threo-, Ai3-51715, Brn 2826438, CAP-palmitate, Cap-P, Chlorambon, Chloramphenicol monopalmitate, Chloramphenicol monopalmitate (ester), Chloramphenicol palmitate (ester), Chloramphenicol palmitate [JAN], Chloramphenicol α-palmitate, Chloromycetin palmitate, Chloropal, Clorolifarina, D-threo-(-)-2,2-Dichloro-N-(beta-hydroxy-alpha-(hydroxymethyl)-p-nitrophenethyl)acetamide alpha-palmitate, Detreopal, Hexadecanoic acid, (2R,3R)-2-[(2,2-dichloroacetyl)amino]-3-hydroxy-3-(4-nitrophenyl)propyl ester, Hexadecanoic acid, (2R,3R)-2-[(dichloroacetyl)amino]-3-hydroxy-3-(4-nitrophenyl)propyl ester, Hexadecanoic acid, 2-((2,2-dichloroacetyl)amino)-3-hydroxy-3-(4-nitrophenyl)propyl ester, (R-(R*,R*))-, Hexadecanoic acid, 2-((dichloroacetyl)amino)-3-hydroxy-3-(4-nitrophenyl)propyl ester, (R-(R*,R*))-, Palmitic acid, alpha-ester with D-threo-(-)-2,2-dichloro-N-(beta-hydroxy-alpha-(hydroxymethyl)-p-nitrophenethyl)acetamide, Palmitic acid, ester with chloramphenicol, Palmitic acid, α-ester with <span class="text-smallcaps">D</span>-threo-(-)-2,2-dichloro-N-[β-hydroxy-α-(hydroxymethyl)-p-nitrophenethyl]acetamide, Unii-43Vu4207Nw, 4-13-00-02753 (Beilstein Handbook Reference), Palmitic acid, α-ester with D-threo-(-)-2,2-dichloro-N-[β-hydroxy-α-(hydroxymethyl)-p-nitrophenethyl]acetamide, Chloramphenicol palmitate

Description

Stability Hygroscopic
Applications Chloramphenicol Palmitate is a Chloramphenicol (C325030) derivative, a broad spectrum antibiotic obtained from cultures of the soil bacterium Streptomyces venezuelae. It has a broad spectrum of activity against Gram-positive and gram-negative bacteria. Antibacterial; antirickettsial.
References Bartz, et al.: J. Biol. Chem., et al.: 172, 445 (1948), Gottlieb, et al.: J. Bacteriol., 55, 409 (1948), Szulczewski, D., et al.: Anal. Profiles Drug Subs., 4, 47 (1975), Price, A., et al.: J. Antibiot., 43, 118 (1981), Shalit, I., et al.: Drugs, 28, 281 (1984),

• Brand: TRC

Chemical properties

• Molecular weight: 561.54
• Formula: C₂₇H₄₂Cl₂N₂O₆
• Color/Form: Off-White
• InChI: InChI=1S/C27H42Cl2N2O6/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-24(32)37-20-23(30-27(34)26(28)29)25(33)21-16-18-22(19-17-21)31(35)36/h16-19,23,25-26,33H,2-15,20H2,1H3,(H,30,34)/t23-,25-/m1/s1
• SMILES: CCCCCCCCCCCCCCCC(=O)OC[C@@H](NC(=O)C(Cl)Cl)[C@H](O)c1ccc([N+](=O)[O-])cc1