Chlormadinone Acetate

CAS: 302-22-7

Ref. TR-C343500

Product Information

• Name: Chlormadinone Acetate
• Synonyms: Pregna-4,6-diene-3,20-dione, 6-chloro-17-hydroxy-, acetate (6CI,7CI,8CI), 17-Acetoxy-6-chloro-6-dehydroprogesterone, 17-Acetoxy-6-chloropregna-4,6-diene-3,20-dione, 6-Chloro-17-acetoxy-4,6-pregnadiene-3,20-dione, 6-Chloro-17-hydroxypregna-4,6-diene-3,20-dione acetate, 6-Chloro-6,7-dehydro-17-acetoxyprogesterone, 6-Chloro-6-dehydro-17-acetoxyprogesterone, Ay 13390-6, Bellissima, Bovisynchron, CAP, Cero, Chlormadinon acetate, Chronosyn, Clordion, Cyclonorm, Fertiletten, Gestafortin, Lormin, Luteran, Lutinyl, Lutoral, Lutoral (Syntex), Matrol, Menstridyl, NSC 92338, Natrol, Normenon, Prostal, RS 1280, Retex, Skedule TM, Synchrosyn, Synchrosyn P, Traslan, Verton, 17-(Acetyloxy)-6-chloropregna-4,6-diene-3,20-dione, 17alpha-Acetoxy-6-chloro-4,6-pregnadiene-3,20-dione, 17alpha-Acetoxy-6-chloro-6,7-dehydroprogesterone, 6-Chloro-17alpha-acetoxy-4,6-pregnadiene-3,20-dione, 6-Chloro-17alpha-hydroxy-4,6-pregnadiene-3,20-dione 17-acetate, 6-Chloro-17alpha-hydroxy-Delta6-progesterone acetate, 6-Chloro-17alpha-hydroxypregna-4,6-diene-3,20-dione acetate, 6-Chloro-6-dehydro-17alpha-acetoxyprogesterone, 6-Chloro-pregna-4,6-dien-17alpha-ol-3,20-dione acetate, 6-Chloro-Delta4,6-pregnadien-17alpha-ol-3,20-dione 17-acetate, 6-Chloro-Delta6-17-acetoxyprogesterone, 6-Chloro-Delta6-[17alpha]acetoxyprogesterone, 6-Chloro-Delta6-dehydro-17-acetoxyprogesterone, 6-Dehydro-6-chloro-17alpha-acetoxyprogesterone, (8Xi,9Xi,14Xi)-6-Chloro-3,20-Dioxopregna-4,6-Dien-17-Yl Acetate, 17-Acetoxy-6-Chloro-6-Dehydroprogesterone, 17α-Acetoxy-6-chloro-4,6-pregnadiene-3,20-dione, 17α-Acetoxy-6-chloro-6,7-dehydroprogesterone, 6-Chloro-17α-acetoxy-4,6-pregnadiene-3,20-dione, 6-Chloro-17α-hydroxy-4,6-pregnadiene-3,20-dione 17-acetate, 6-Chloro-17α-hydroxy-Δ6-progesterone acetate, 6-Chloro-17α-hydroxy-Δ⁶-progesterone acetate, 6-Chloro-17α-hydroxypregna-4,6-diene-3,20-dione acetate, 6-Chloro-3,20-Dioxopregna-4,6-Dien-17-Yl Acetate, 6-Chloro-6-dehydro-17α-acetoxyprogesterone, 6-Chloro-pregna-4,6-dien-17α-ol-3,20-dione acetate, 6-Chloro-Δ4,6-pregnadien-17α-ol-3,20-dione 17-acetate, 6-Chloro-Δ6-17-acetoxyprogesterone, 6-Chloro-Δ6-[17α]acetoxyprogesterone, 6-Chloro-Δ6-dehydro-17-acetoxyprogesterone, 6-Chloro-Δ^4,6-pregnadien-17α-ol-3,20-dione 17-acetate, 6-Chloro-Δ⁶-17-acetoxyprogesterone, 6-Chloro-Δ⁶-[17α]acetoxyprogesterone, 6-Chloro-Δ⁶-dehydro-17-acetoxyprogesterone, 6-Dehydro-6-chloro-17α-acetoxyprogesterone, Acetate De Chlormadinone, Acetato De Clormadinona, Chloramdinone acetate, Chlormadinonacetat, Chloromadinone acetate, Nsc 92338, Pregna-4,6-diene-3,20-dione, 17-(acetyloxy)-6-chloro-, Pregna-4,6-diene-3,20-dione, 6-chloro-17-hydroxy-, acetate, Rs 1280

Description

Applications Orally active progesteron with antiandrogenic activity; has been used in combinations as an oral contraceptive. Progestogen; antineoplastic (hormonal).
References Brennan, D.M., et al.: Acta Endocrinol., 44, 367 (1963), Honma., s., et al.: Chem Pharm. Bull., 25 2019 (1977), Usui, T., et al.: Acta Urol. Jpn., 27, 327 (1981),

• Brand: TRC

Chemical properties

• Molecular weight: 404.93
• Formula: C₂₃H₂₉ClO₄
• Color/Form: Neat
• InChI: InChI=1S/C23H29ClO4/c1-13(25)23(28-14(2)26)10-7-18-16-12-20(24)19-11-15(27)5-8-21(19,3)17(16)6-9-22(18,23)4/h11-12,16-18H,5-10H2,1-4H3/t16-,17+,18+,21-,22+,23+/m1/s1
• InChI key: InChIKey=QMBJSIBWORFWQT-VDOKUWMYSA-N
• SMILES: CC(=O)OC1(C(C)=O)CC[C@H]2[C@@H]3C=C(Cl)C4=CC(=O)CC[C@]4(C)[C@@H]3CC[C@@]21C