5-Chloro-6-((o-tolyamino)methyl)quinazoline-2,4-diamine

CAS: 59-30-3

Ref. TR-C347705

Product Information

• Name: 5-Chloro-6-((o-tolyamino)methyl)quinazoline-2,4-diamine
• Synonyms: 5-chloro-6-[(2-methylanilino)methyl]quinazoline-2,4-diamine, (2R)-2-[(4-{[(2-amino-4-oxo-1,4-dihydropteridin-6-yl)methyl]amino}benzoyl)amino]pentanedioate, (2S)-2-[(4-[[(2-Amino-4-hydroxypteridin-6-yl)methyl]amino]phenyl)formamido]pentanedioic acid, (2S)-2-[[4-[(2-Amino-4-oxo-1H-pteridin-6-yl)methylamino]benzoyl]amino]pentanedioic acid, 2-Amino-6-((P-((1,3-Dicarboxypropyl)Carbamoyl)Anilino)Methyl)-4-Pteridinol, 4-(2-amino-4-oxopteridin-6-yl) methylaminobenzoyl-L-glutamic acid, <span class="text-smallcaps">L</span>-Glutamic acid, N-[4-[[(2-amino-1,4-dihydro-4-oxo-6-pteridinyl)methyl]amino]benzoyl]-, <span class="text-smallcaps">L</span>-Glutamic acid, N-[4-[[(2-amino-3,4-dihydro-4-oxo-6-pteridinyl)methyl]amino]benzoyl]-, Acide folique, Acido Folico, Acifolic, Aspol, Cytofol, Dosfolat B activ, Dosfolat XS, Folacid, Folacin, Folbal, Folcidin, Folcysteine, Foldine, Folettes, Foliamin, Folic acidBP/USP, Kosher certificate, Folicet, Folipac, Folnak, Folovit, Folsan, Folsaure, Folsav, Foluite, Folvite, Incafolic, L-Glutamic Acid, N-(4-(((2-Amino-1,4-Dihydro-4-Oxo-6-Pteridinyl)Methyl)Amino)Benzoyl)-, L-Glutamic acid, N-[4-[[(2-amino-3,4-dihydro-4-oxo-6-pteridinyl)methyl]amino]benzoyl]-, L-pteroylglutamic acid, Liver Lactobacillus Casei Factor, Millafol, N-(4-(((2-amino-1,4-dihydro-4-oxo-6-pteridinyl)methyl)amino)benzoyl)-L-glutamic acid, N-(4-{[(2-amino-4-oxo-1,4-dihydropteridin-6-yl)methyl]amino}benzoyl)-L-glutamic acid, N-(4-{[(2-amino-4-oxo-1,4-dihydropteridin-6-yl)methyl]amino}benzoyl)glutamic acid, N-(p-(((2-amino-4-hydroxy-6-pteridinyl)methyl)amino)benzoyl)-L-glutamic acid, N-4-[(2-Amido-4-oxo-1,4-dihydro-6-terene) methyl amino] benzoyl-L-glutamic acid, N-4-[(2-Amido-4-oxo-1,4-dihydro-6-terene)methylamino]benzoyl-L-glutamic acid, N-[4-[[(2-Amino-3,4-dihydro-4-oxo-6-pteridinyl)methyl]amino]benzoyl]-<span class="text-smallcaps">L</span>-glutamic acid, N-[4-[[(2-Amino-4-Hydroxy-6-Pteridyl)Methyl]Amino]Benzoyl]Glutamic Acid, Nsc 3073, PGA, Pteglu, Pteroyl-<span class="text-smallcaps">L</span>-glutamic acid, Pteroyl-<span class="text-smallcaps">L</span>-monoglutamic acid, Pteroylglutamic acid, Pteroylmonoglutamic Acid, Vitamin B, Vitamin B11, Vitamin B₉, Vitamin B_c, Vitamin B_e, Vitamin BC, Vitamin Be, Vitamin M, pteroyl-L-glutamic acid, pteroyl-L-monoglutamic acid

Description

Applications 5-Chloro-6-((o-tolyamino)methyl)quinazoline-2,4-diamine s an analogue of folic acid (F680300) which is a vitamin needed to synthesize DNA, conduct DNA repair and methylate DNA, it also acts as a cofactor in biological reactions involving folate.
References Xu, L., et al.: Mol. Pharm., 7, 1311 (2010), Everette, J., et al.: J. Agric. Food Chem., 58, 8139 (2010), Alshatwi, A., et al.: Food, Chem., Toxicol., 48, 1881 (2010), McKay, D., et al.: Nut. J., 9 (2010),

• Brand: TRC

Chemical properties

• Molecular weight: 313.785
• Formula: C₁₆H₁₆ClN₅
• Color/Form: Neat
• InChI: InChI=1S/C16H16ClN5/c1-9-4-2-3-5-11(9)20-8-10-6-7-12-13(14(10)17)15(18)22-16(19)21-12/h2-7,20H,8H2,1H3,(H4,18,19,21,22)
• InChI key: InChIKey=BXBPOHNZKGEMCT-UHFFFAOYSA-N
• SMILES: Cc1ccccc1NCc1ccc2nc(N)nc(N)c2c1Cl