5-Chloro-2-furancarbonyl Fluticasone Furoate

Ref. TR-C357630

Product Information

• Name: 5-Chloro-2-furancarbonyl Fluticasone Furoate
• Synonyms: Fluticasone Impurity 30, 5-Chloro-Furoyl Fluticasone Furoate
• Brand: TRC
• Description: Applications 5-Chloro-2-furancarbonyl Fluticasone Furoate is a Fluticasone Furoate(F599510) raw material impurity which is a synthetic corticosteroid derived from fluticasone for treatment of seasonal allergic rhinitis.References DeWester, J., et al.: Allergy Asthma Proc., 24, 331 (2003), Hughes, S., et al.: Drug Metab. Dispos., 36, 2337 (2008), Meltzer, E., et al.: Clin. Drug Investig., 29, 79 (2009),

Chemical properties

• Molecular weight: 573.02
• Formula: C₂₇H₂₈ClF₃O₆S
• Color/Form: Neat
• InChI: InChI=1S/C27H28ClF3O6S/c1-13-8-15-16-10-18(30)17-9-14(32)6-7-24(17,2)26(16,31)20(33)11-25(15,3)27(13,23(35)38-12-29)37-22(34)19-4-5-21(28)36-19/h4-7,9,13,15-16,18,20,33H,8,10-12H2,1-3H3/t13-,15+,16+,18+,20+,24+,25+,26+,27+/m1/s1
• InChI key: InChIKey=ITHYWEVATCRTPS-KOYUWZPRSA-N
• SMILES: C[C@@H]1C[C@H]2[C@@H]3C[C@H](F)C4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@]2(C)[C@@]1(OC(=O)c1ccc(Cl)o1)C(=O)SCF