4-Chloro-2-(4-chlorobenzoyl)-1-(4-methoxyphenyl)hydrazide Benzoic Acid
CAS:
Ref. TR-C365540
50mg
138.00€
100mg
201.00€
2500mg
2,014.00€
Product Information
Name:4-Chloro-2-(4-chlorobenzoyl)-1-(4-methoxyphenyl)hydrazide Benzoic Acid
Synonyms:
- Benzoic acid
- 4-chloro-
- 2-(4-chlorobenzoyl)-1-(4-methoxyphenyl)hydrazide
- 4-Chloro-N'-(4-chlorobenzoyl)-N-(4-methoxyphenyl)benzohydrazide
- Indometacin dibenzylate
Brand:TRC
Description:Applications An impurity of the anti-inflammatory drug indomnethacin (I641000). Indomethacin inhibits cyclooxygenase (IC50=0.1uM) selectively over liposygenases (IC50=100uM for 5-,12- and 15-LO). A clinically useful NAISD.References Salari, H., et al.: Prostagland. Leukotrienes Med., 13, 53 (1984), Lehmann, J.M., et al.: J. Biol. Chem., 272, 3406 (1997)
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Chemical properties
Molecular weight:415.27
Formula:C21H16Cl2N2O3
Color/Form:Neat
InChI:InChI=1S/C21H16Cl2N2O3/c1-28-19-12-10-18(11-13-19)25(21(27)15-4-8-17(23)9-5-15)24-20(26)14-2-6-16(22)7-3-14/h2-13H,1H3,(H,24,26)
InChI key:InChIKey=GSKPJTLOCASRRI-UHFFFAOYSA-N
SMILES:COc1ccc(N(NC(=O)c2ccc(Cl)cc2)C(=O)c2ccc(Cl)cc2)cc1
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