3-(2-Chloroethyl)-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one

CAS: 41078-70-0

Ref. TR-C366150

Product Information

• Name: 3-(2-Chloroethyl)-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one
• Synonyms: 4H-Pyrido[1,2-a]pyrimidin-4-one, 3-(2-chloroethyl)-2-methyl-, 3-(2-Chloroethyl)-2-methylpyrido[1,2-a]pyrimidin-4-one
• Brand: TRC
• Description: Applications An intermediate in the synthesis of Risperidone (R525000), which is a combined serotonin (5-HT2) and dopamine (D2) receptor antagonist. Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the packageReferences Brown, T., et al.: J. Med. Chem., 33, 527 (1990), Yapi, A., et al.: Chem. Pharm. Bull., 48, 1886 (2000), Yapi, A., et al.: Arch. Pharm., 339, 201 (2006); Jannssen, P.A.J., et al.: J. Pharmacol. Exp. Ther., 244, 685 (1988); Gelders, Y.G., et al.: Pharmacopsychiatry, 23, 206 (1990); Green, B.: Curr. Med. Res. Opin., 16, 57 (2000)

Chemical properties

• Molecular weight: 222.67
• Formula: C₁₁H₁₁ClN₂O
• Color/Form: Neat
• InChI: InChI=1S/C11H11ClN2O/c1-8-9(5-6-12)11(15)14-7-3-2-4-10(14)13-8/h2-4,7H,5-6H2,1H3
• InChI key: InChIKey=LFTGLYCNMGGMKL-UHFFFAOYSA-N
• SMILES: Cc1nc2ccccn2c(=O)c1CCCl