Product Information
Name:2-Chlorotetrahydro-2-oxo-2H-1,3,2-oxazaphosphorin
Controlled Product
Synonyms:
- 2-Chloro-1,3,2-oxazaphosphacyclohexane 2-Oxide
Brand:TRC
Description:Applications 2-Chlorotetrahydro-2-oxo-2H-1,3,2-oxazaphosphorin is an intermediate in the synthesis of N-Dides(2-chloroethyl) N-(2-Hydroxyethyl),N-(2-ethoxyethyl) Cyclophosphamide (C984610) which is a derivative of Cyclophosphamide Monohydrate (C988580), a known human carcinogen that is widely used in cancer chemotherapy because it can cross-link DNA causing strand breakage and mutation.References Wheeler, A.G., et al.: Toxicol. Appl. Pharmacol., 4, 324 (1962), Fraiser, L.H., et al.: Drugs, 42, 781 (1991), Colvin, O.M., et al.: Curr. Pharmaceut. Design, 5, 555 (1999)
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:155.52
Formula:C3H7ClNO2P
Color/Form:Neat
InChI:InChI=1S/C3H7ClNO2P/c4-8(6)5-2-1-3-7-8/h1-3H2,(H,5,6)
InChI key:InChIKey=KTJQXXIVWRXBCC-UHFFFAOYSA-N
SMILES:O=P1(Cl)NCCCO1
Technical inquiry about: 2-Chlorotetrahydro-2-oxo-2H-1,3,2-oxazaphosphorin
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