Product Information
Name:4-Chloro Kynurenine-13C2,15N
Controlled Product
Synonyms:
- α,2-Diamino-4-chloro-γ-oxobenzenebutanoic Acid-13C2,15N
- (+/-)-α,2-Diamino-4-chloro-γ-oxobenzenebutanoic Acid-13C2,15N
- 4-Cl-KYN-13C2,15N
- (+/-)-AV-101-13C2,15N
Brand:TRC
Description:Applications 7-Cl-kynurenic acid (7-Cl-KYNA) is a potent, selective antagonist of the NMDA/glycine receptor but penetrates poorly through the blood-brain barrier. Its prodrug, L-4-Cl-kynurenine (4-Cl-KYN), readily enters the brain from the circulation and provides antiexcitotoxic neuroprotection after systemic application.References Leeson, P., et al.: J. Med. Chem., 37, 4053 (1994), Hilmas, C., et al.: J. Neurosci., 2001, 21, 7463 (2001), Palmer, G., et al.: Curr. Drug Targets, 2, 241 (2001), Wu, H., et al.: Exp. Neurol., 177, 222 (2002),
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:245.64
Formula:C813C2H11ClN15NO3
Color/Form:Neat
InChI:InChI=1S/C10H11ClN2O3/c11-5-1-2-6(7(12)3-5)9(14)4-8(13)10(15)16/h1-3,8H,4,12-13H2,(H,15,16)/i8+1,10+1,13+1
InChI key:InChIKey=HQLHZNDJQSRKDT-SVKOXWCPSA-N
SMILES:Nc1cc(Cl)ccc1C(=O)C[13CH]([15NH2])[13C](=O)O
Technical inquiry about: 4-Chloro Kynurenine-13C2,15N
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