2-Chlorobenzonitrile

CAS: 873-32-5

Ref. TR-C367330

Product Information

• Name: 2-Chlorobenzonitrile
• Synonyms: Benzonitrile, o-chloro- (7CI,8CI), 1-Chloro-2-cyanobenzene, 2-Chlorophenyl cyanide, 2-Cyanochlorobenzene, 2-Cyanostyrene, NSC 8438, o-Chlorobenzonitrile, o-Chlorocyanobenzene, o-Cyanochlorobenzene, Benzonitrile, 2-chloro-, Benzonitrile, o-chloro-, O-Chlorobenzonitrile, Ocbn

Description

Applications 2-Chlorobenzonitrile is an activated aryl chloride that is commonly used in reactions that involve the Palladium-catalyzed direct arylation of heteroaromatics (e.g. 3-aminopicolinic acid [A627800]). 2-Chlorobenzonitrile and its substituted derivatives (e.g. 2,3-dichloro-6-nitrobenzonitrile [2112-22-3]) also have potential anti-inflammatory properties.
References Andreu, M., et al.: Chem. Commun., 24, 2475 (2000); Hellman, W., et al.: J. Med. Chem., 21, 906 (1978); Roy, D., et al.: ACS Catal., 2, 1033 (2012);

• Brand: TRC

Chemical properties

• Molecular weight: 137.57
• Formula: C₇H₄ClN
• Color/Form: Neat
• InChI: InChI=1S/C7H4ClN/c8-7-4-2-1-3-6(7)5-9/h1-4H
• InChI key: InChIKey=IBSQPLPBRSHTTG-UHFFFAOYSA-N
• SMILES: N#Cc1ccccc1Cl