4-Chloro-1-(4-methoxyphenoxy)-2-nitrobenzene
CAS: 62966-77-2
Ref. TR-C368745
| 1g | Discontinued | ||
| 10g | Discontinued |
Product Information
Name:
4-Chloro-1-(4-methoxyphenoxy)-2-nitrobenzene
Synonyms:
- 4-Chloro-2-nitrophenyl 4-methoxyphenyl Ether
Description:
Applications 4-Chloro-1-(4-methoxyphenoxy)-2-nitrobenzene is used in the preparation of Amino Hydroxynimesulide (A618310), an analog of Nimesulide (N477500), an antiinflammatory agent. Preferentially inhibits COX-2 over COX-1. Suppresses chemical-induced carcinogenesis in mice and rats. Inhibits LPS-induced TNF-alpha production.
References Pairet, M., et al.: Inflamm. Res., 47, S93 (1998), Fukutake, M., et al.: Carcinogenesis, 19, 1939 (1998), Okajima., E., et al.: Cancer Res., 58, 3028 (1998), Azab, A., et al.: Life Sci., 63, 323 (1998); Li, F. et al.: Chem. Res. Toxicol., 22, 72 (2009);
Notice:
Our products are intended for lab use only. For any other use, please contact us.
Brand:
TRC
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Chemical properties
Molecular weight:
279.68
Formula:
C13H10ClNO4
InChI:
InChI=1S/C13H10ClNO4/c1-18-10-3-5-11(6-4-10)19-13-7-2-9(14)8-12(13)15(16)17/h2-8H,1H3
SMILES:
COc1ccc(Oc2ccc(Cl)cc2[N+](=O)[O-])cc1
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