Product Information
Name:2-Chloro-5-nitropyrimidin-4-ol
Controlled Product
Synonyms:
- 2-Chloro-5-nitro-4(3H)-pyrimidinone
- 2-Chloro-5-nitro-4(1H)-pyrimidinone
Brand:TRC
Description:Applications 2-Chloro-5-nitropyrimidin-4-ol is an intermediate used in the synthesis of 4-Chloro-5-nitro-2-(propylthio)pyrimidine (C374095), which is an impurity of the drug Ticagrelor (T437700), the first reversible oral P2Y12 receptor antagonist, provides faster, greater, and more consistent ADP-receptor inhibition than Clopidogrel. Ticagrelor is used in the treatment of acute coronary syndromes (ACS).References Matetzky, S., et al.: Circulation, 109, 3171 (2004), Bassand, J., et al.: Eur. Heart J., 28, 1598 (2007), Jakubowski, J., et al.: Cardiovasc. Drug Rev., 25, 357 (2007)
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:175.53
Formula:C4H2ClN3O3
Color/Form:Neat
InChI:InChI=1S/C4H2ClN3O3/c5-4-6-1-2(8(10)11)3(9)7-4/h1H,(H,6,7,9)
SMILES:O=[N+]([O-])c1cnc(Cl)nc1O
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