4-(2-Chlorophenyl)-2-[[2-(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)ethoxy]methyl]-1,4-dihydro-6-methyl-3,5-pyridinedicarboxylic Acid 3,5-Dimethyl Ester

CAS: 140171-50-2

Ref. TR-C376585

Product Information

• Name: 4-(2-Chlorophenyl)-2-[[2-(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)ethoxy]methyl]-1,4-dihydro-6-methyl-3,5-pyridinedicarboxylic Acid 3,5-Dimethyl Ester
• Synonyms: 3,5-Pyridinedicarboxylic acid, 4-(2-chlorophenyl)-2-[[2-(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)ethoxy]methyl]-1,4-dihydro-6-methyl-, 3,5-dimethyl ester (ACI), 3,5-Dimethyl 4-(2-chlorophenyl)-2-[[2-(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)ethoxy]methyl]-1,4-dihydro-6-methyl-3,5-pyridinedicarboxylate (ACI), 3,5-Pyridinedicarboxylic acid, 4-(2-chlorophenyl)-2-[[2-(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)ethoxy]methyl]-1,4-dihydro-6-methyl-, dimethyl ester (9CI), 4-(2-Chlorophenyl)-2-[[2-(1,3-dioxo-1,3-dihydroisoindol-2-yl)ethoxy]methyl]-6-methyl-1,4-dihydropyridine-3,5-dicarboxylic acid dimethyl ester
• Brand: TRC
• Description: Applications 4-(2-Chlorophenyl)-2-[[2-(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)ethoxy]methyl]-1,4-dihydro-6-methyl-3,5-pyridinedicarboxylic Acid 3,5-Dimethyl Ester is an intermediate in the synthesis of Amlodipine Besilate (A633500) related compounds.References Alker, D., et al.: Eur. J. Med. Chem., 26, 907 (1991)

Chemical properties

• Molecular weight: 524.95
• Formula: C₂₇H₂₅ClN₂O₇
• Color/Form: Neat
• InChI: InChI=1S/C27H25ClN2O7/c1-15-21(26(33)35-2)22(18-10-6-7-11-19(18)28)23(27(34)36-3)20(29-15)14-37-13-12-30-24(31)16-8-4-5-9-17(16)25(30)32/h4-11,22,29H,12-14H2,1-3H3
• InChI key: InChIKey=AVJKDKWRVSSJPK-UHFFFAOYSA-N
• SMILES: Fc1ccc(N2CCNCC2)cc1