4-(p-Chloro-alpha-phenylbenzyl)-1-piperazineethanol

CAS: 109806-71-5

Ref. TR-C377565

Product Information

• Name: 4-(p-Chloro-alpha-phenylbenzyl)-1-piperazineethanol
• Synonyms: 1-Piperazineethanol, 4-[(4-chlorophenyl)phenylmethyl]-, 1-Piperazineethanol, 4-(p-chloro-α-phenylbenzyl)- (6CI), 4-[(4-Chlorophenyl)phenylmethyl]-1-piperazineethanol, 2-[4-[(4-Chlorophenyl)phenylmethyl]piperazin-1-yl]ethanol, 2-[4-[(RS)-(4-Chlorophenyl)phenylmethyl]piperazin-1-yl]ethanol
• Brand: TRC

Description

Stability Very Hygroscopic
Applications 4-(p-Chloro-α-phenylbenzyl)-1-piperazineethanol is used in the synthesis of antifungal triazole and imidazole derivatives. Impurity of an intermediate in the formation of Cetrizine.
References Rezaei, Z. et al.: Archiv. Pharm., 344, 658 (2011)

Chemical properties

• Molecular weight: 330.85
• Formula: C₁₉H₂₃ClN₂O
• Color/Form: Neat
• InChI: InChI=1S/C19H23ClN2O/c20-18-8-6-17(7-9-18)19(16-4-2-1-3-5-16)22-12-10-21(11-13-22)14-15-23/h1-9,19,23H,10-15H2
• InChI key: InChIKey=ZJQSBXXYLQGZBR-UHFFFAOYSA-N
• SMILES: OCCN1CCN(C(c2ccccc2)c2ccc(Cl)cc2)CC1