2-Chloro-N-(2,6-dichlorophenyl)-N-phenylacetamide-13C6

CAS: 15308-01-7

Ref. TR-C377626

Product Information

• Name: 2-Chloro-N-(2,6-dichlorophenyl)-N-phenylacetamide-13C6
• Synonyms: 2,2',6'-Trichloro-N-phenylacetanilide-13C6, N-(Chloroacetyl)-2,6-dichlorodiphenylamine-13C6, 2,2′,6′-Trichloro-N-phenylacetanilide, Acetamide, 2-chloro-N-(2,6-dichlorophenyl)-N-phenyl-, Acetanilide, 2,2′,6′-trichloro-N-phenyl-, N-(2,6-2 Chlorophenyl)-N-phenyl-Chloroacetamide, N-(Chloroacetyl)-2,6-dichlorodiphenylamine
• CAS: 15308-01-7

Description

Applications 2-Chloro-N-(2,6-dichlorophenyl)-N-phenylacetamide-13C6 is an intermediate in the synthesis of Diclofenac-13C6 (D436449). Diclofenac-13C6 is a labelled analogue of Diclofenac Acid (D436465), which is a nonsteroidal anti-inflammatory compound and decycloxygenase (COX) inhibitor. Diclofenac-13C6 is also an intermediate in synthesizing Diclofenac-13C6 Sodium Salt (D436453), which is a labelled analogue of Diclofenac Sodium Salt (D436450).
References Yagi, K., et. al.: Biol. Pharm. Bull., 37, 1234 (2014); Kenny, J. R., et al.: J. Med. Chem., 47, 2816 (2004); Sasaki, A., et al.: J. Pharmacol. Sci., 108, 266 (2008); Dalvie, D., et al.: Chem. Res. Toxicol., 22, 357 (2009); Kenny, J. R., et al.: J. Med. Chem., 47, 2816 (2004), Sasaki, A., et al.: J. Pharmacol. Sci., 108, 266 (2008); Dalvie, D., et al.: Chem. Res. Toxicol., 22, 357 (2009)

• Brand: TRC

Chemical properties

• Molecular weight: 320.55
• Formula: C₈C₆H₁₀Cl₃NO
• Color/Form: Neat
• InChI: InChI=1S/C14H10Cl3NO/c15-9-13(19)18(10-5-2-1-3-6-10)14-11(16)7-4-8-12(14)17/h1-8H,9H2/i1+1,2+1,3+1,5+1,6+1,10+1
• InChI key: InChIKey=BPEUHDIEZQWRGC-CSPPZNRPSA-N
• SMILES: O=C(CCl)N(c1c(Cl)cccc1Cl)[13c]1[13cH][13cH][13cH][13cH][13cH]1