Estimated delivery in United States, on Wednesday 8 Jan 2025
Product Information
Name:
5-Chloro-2-nitroanisole
Controlled Product
Synonyms:
- 4-Chloro-2-methoxy-1-nitrobenzene
- 1-Chloro-3-methoxy-4-nitrobenzene
- 2-Methoxy-4-chloronitrobenzene
- 2-Nitro-5-chloroanisole
- 3-Methoxy-4-nitro-1-chlorobenzene
- 4-Chloro-2-(methyloxy)-1-nitrobenzene
- 4-Chloro-2-methoxy-1-nitrobenzene
- 4-Chloro-2-methoxynitrobenzene
- 5-Chloro-2-nitrophenyl Methyl Ether
- NSC 60112
- See more synonyms
- 5-Chloro-2-nitrophenyl methyl ether
- Anisole, 5-chloro-2-nitro-
- Benzene, 4-chloro-2-methoxy-1-nitro-
Description:
Applications 5-Chloro-2-nitroanisole is involved in the synthesis of orally bioavailable anaplastic lymphoma kinases (ALK) inhibitors as anticancer drugs (1). In addition, it is used in the synthesis of kinesin spindle protein (KSP) inhibitors which are responsible for the spindle pole separation which occurs during mitosis in cancer cells (2).
References (1) Mesaros, E. et al.: J. Med. Chem. (2012) 55, 115-25 (2) Parrish, C. A., et al.: J. Med. Chem. (2007) 50, 4939-50
Notice:
Our products are intended for lab use only. For any other use, please contact us.
Brand:
TRC
Long term storage:
Notes:
Chemical properties
Molecular weight:
187.58
Formula:
C7H6ClNO3
Color/Form:
Neat
SMILES:
COc1cc(Cl)ccc1[N+](=O)[O-]
MDL:
Melting point:
Boiling point:
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Density:
Concentration:
EINECS:
Merck:
HS code:
Technical inquiry about: TR-C377695 5-Chloro-2-nitroanisole
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