4-epi-Chlortetracycline Hydrochloride (>90% by HPLC)

CAS: 101342-45-4

Ref. TR-C426501

Product Information

• Name: 4-epi-Chlortetracycline Hydrochloride (>90% by HPLC)
• Synonyms: 4-epi-Chlortetracycline Hydrochloride, Chlortetracycline Imp. A (EP), 2-Naphthacenecarboxamide, 7-chloro-4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-, hydrochloride (1:1), (4R,4aS,5aS,6S,12aS)-, 2-Naphthacenecarboxamide, 7-chloro-4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-, monohydrochloride, (4R,4aS,5aS,6S,12aS)- (9CI), 2-Naphthacenecarboxamide, 7-chloro-4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-, monohydrochloride, [4R-(4a,4aß,5aß,6a,12aß)]-, 4-Epichlortetracycline hydrochloride, Ectc

Description

Stability Hygroscopic, Unstable in Solution
Applications A Tetracycline derivative. It is a metalloprotease inhibitor used in treating tissue destructive diseases and cancer.
References Golub, et al.: J. Periodont. Res., 20, 12 (1985), Maragoudakis, et al.: Br. J. Pharmacol., 111, 894 (1994),

• Brand: TRC

Chemical properties

• Molecular weight: 515.34
• Formula: C₂₂H₂₃ClN₂O₈·ClH
• Purity: >90% by HPLC
• Color/Form: Yellow
• InChI: InChI=1S/C22H23ClN2O8.ClH/c1-21(32)7-6-8-15(25(2)3)17(28)13(20(24)31)19(30)22(8,33)18(29)11(7)16(27)12-10(26)5-4-9(23)14(12)21;/h4-5,7-8,15,26,28-29,32-33H,6H2,1-3H3,(H2,24,31);1H/t7-,8-,15+,21-,22-;/m0./s1
• InChI key: InChIKey=CBHYYLPALVVVEY-FYRLHVCPSA-N
• SMILES: CN(C)[C@H]1C(O)=C(C(N)=O)C(=O)[C@@]2(O)C(O)=C3C(=O)c4c(O)ccc(Cl)c4[C@@](C)(O)C3C[C@@H]12.Cl