2-Chloro-N6-cyclopentyl-d4 Adenosine

CAS: 37739-05-2

Ref. TR-C427652

Product Information

• Name: 2-Chloro-N6-cyclopentyl-d4 Adenosine
• Synonyms: (2R,3R,4S,5R)-2-[2-chloro-6-[(3,3,4,4-tetradeuteriocyclopentyl)amino]purin-9-yl]-5-(hydroxymethyl)oxolane-3,4-diol, (2R,3R,4S,5R)-2-[2-Chloro-6-(cyclopentylamino)-9H-purin-9-yl]-5-(hydroxymethyl)tetrahydrofuran-3,4-diol, 2-Chloro-N(6)cyclopentyladenosine, 2-Chloro-N⁶-cyclopentyladenosine, 2-chloro-N-cyclopentyladenosine, Adenosine, 2-chloro-N-cyclopentyl-, Brn 4888162

Description

Applications Labelled 2-Chloro-N6-cyclopentyl Adenosine (C4276500. Adenosine receptors are for treating central nervous system (CNS) disorders. Adenosine A1 receptor agonists include e.g. CCPA, 8-cyclopentyl-1,3-dipropylxanthine, R-phenylisopropyl adenosine. A2A receptor agonists include e.g. regadenoson (Lexiscan), apadenoson, binodenoson.
References Arch, J., et al.: Biochem. J., 174, 965 (1978), Agnati, L., et al.: Pharmacol. Rev., 55, 509 (2003), Badman, M., et al.: Science, 307, 1909 (2005),

• Brand: TRC

Chemical properties

• Molecular weight: 373.828
• Formula: C₁₅D₄H₁₆ClN₅O₄
• Color/Form: Neat
• InChI: InChI=1S/C15H20ClN5O4/c16-15-19-12(18-7-3-1-2-4-7)9-13(20-15)21(6-17-9)14-11(24)10(23)8(5-22)25-14/h6-8,10-11,14,22-24H,1-5H2,(H,18,19,20)/t8-,10-,11-,14-/m1/s1/i1D2,2D2
• InChI key: InChIKey=XSMYYYQVWPZWIZ-BTRUMVDQSA-N
• SMILES: [2H]C1([2H])CC(Nc2nc(Cl)nc3c2ncn3[C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)CC1([2H])[2H]