4-Chloro-2-methylbenzoic Acid

CAS: 7499-07-2

Ref. TR-C427685

Product Information

• Name: 4-Chloro-2-methylbenzoic Acid
• Synonyms: 4-Chloro-o-toluic Acid, NSC 407521

Description

Applications 4-Chloro-2-methylbenzoic Acid is used as a reagent in organic synthesis including that of diarylamides which have a pyrimidinyl pyridine scaffold which show promising anti-proliferative effects on melanoma cancer cell lines. It is also used in the preparation of analogs of lenalidomide and pomalidomide for use as anti inflammatory and antitumor agents.
References Abdelazem, A., et al.: Bioorg. Med. Chem. Lett., 26, 1301 (2016); Ruchelman, A., et al.: Bioorg. Med. Chem. Lett., 23, 360 (2013);

• Brand: TRC

Chemical properties

• Molecular weight: 170.59
• Formula: C₈H₇ClO₂
• Color/Form: Neat
• InChI: InChI=1S/C8H7ClO2/c1-5-4-6(9)2-3-7(5)8(10)11/h2-4H,1H3,(H,10,11)
• InChI key: InChIKey=XXFKOBGFMUIWDH-UHFFFAOYSA-N
• SMILES: Cc1cc(Cl)ccc1C(=O)O