![4-Chloro-6-[2-(1,1-dimethylethoxy)ethoxy]-5-(2-methoxyphenoxy)-2,2'-bipyrimidine](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FTR%2Fthumb-webp%2FC428995.webp&w=3840&q=75)
4-Chloro-6-[2-(1,1-dimethylethoxy)ethoxy]-5-(2-methoxyphenoxy)-2,2'-bipyrimidine
CAS:
Ref. TR-C428995
100mg
1,022.00€
Product Information
Name:4-Chloro-6-[2-(1,1-dimethylethoxy)ethoxy]-5-(2-methoxyphenoxy)-2,2'-bipyrimidine
Controlled Product
Synonyms:
- 2,2'-Bipyrimidine
- 4-chloro-6-[2-(1,1-dimethylethoxy)ethoxy]-5-(2-methoxyphenoxy)-
Brand:TRC
Description:Impurity BosentanApplications 4-Chloro-6-[2-(1,1-dimethylethoxy)ethoxy]-5-(2-methoxyphenoxy)-2,2'-bipyrimidine is an impurity of Bosentan (B675900). Bosentan is a mixed endothelin receptor antagonist used as a vasodilatora and an antihypertensive.References Clozel, M., et al.: J. Pharmacol. Exp. Ther., 270, 228 (1994); Gutsch, G., et al.: Cardiovasc. Drugs Ther., 10, 717 (1996); Weber, C., et al.: Clin Pharmacol. Ther., 60, 124 (1996); Krum, H., et al.: N. Engl. J. Med., 338, 784 (1998)
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Chemical properties
Molecular weight:430.885
Formula:C21H23ClN4O4
Color/Form:Neat
InChI:InChI=1S/C21H23ClN4O4/c1-21(2,3)29-13-12-28-20-16(30-15-9-6-5-8-14(15)27-4)17(22)25-19(26-20)18-23-10-7-11-24-18/h5-11H,12-13H2,1-4H3
InChI key:InChIKey=JTGXWPPVARCKAG-UHFFFAOYSA-N
SMILES:COc1ccccc1Oc1c(Cl)nc(-c2ncccn2)nc1OCCOC(C)(C)C
Technical inquiry about: 4-Chloro-6-[2-(1,1-dimethylethoxy)ethoxy]-5-(2-methoxyphenoxy)-2,2'-bipyrimidine
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