Estimated delivery in United States, on Friday 10 Jan 2025
Product Information
Name:
Cilastatin-15N-d3
Controlled Product
Synonyms:
- (Z)-7-[(2R)-2-(15N)azanyl-2-carboxy-1,1,2-trideuterioethyl]sulfanyl-2-[[(1S)-2,2-dimethylcyclopropanecarbonyl]amino]hept-2-enoic acid
Description:
Applications (R)-2-Carboxy-2-(S)-ethyl)-thio Cilastatin is a labelled impurity of Cilastatin (C441100) which prevents renal metabolism of penem and carbapenem antibiotics by specific and reversible dehydropeptidase I inhibition. Antibacterial adjunct.
References Finlay, K.R., et al.: Invest. Ophthalmol. Visual Sci., 24, 1147 (1983), Norrby, S.R., et al.: Antimicrob. Agents Chemother., 23, 300 (1983), Washburn, D.E., et al.: J. Antimicrob. Chemother., 12, 39 (1983),
Notice:
Our products are intended for lab use only. For any other use, please contact us.
Brand:
TRC
Long term storage:
Notes:
Chemical properties
Molecular weight:
362.465
Formula:
C16D3H23NNO5S
Color/Form:
White To Off-White
InChI:
InChI=1S/C16H26N2O5S/c1-16(2)8-10(16)13(19)18-12(15(22)23)6-4-3-5-7-24-9-11(17)14(20)21/h6,10-11H,3-5,7-9,17H2,1-2H3,(H,18,19)(H,20,21)(H,22,23)/b12-6-/t10-,11+/m1/s1/i9D2,11D,17+1
InChI key:
InChIKey=DHSUYTOATWAVLW-IFTJZPFKSA-N
SMILES:
[2H]C([2H])(SCCCC/C=C(\NC(=O)[C@@H]1CC1(C)C)C(=O)O)C([2H])([15NH2])C(=O)O
MDL:
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EINECS:
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HS code:
Technical inquiry about: TR-C441101 Cilastatin-15N-d3
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