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Product Information
Name:
Cilastatin Ammonium Salt
Controlled Product
Synonyms:
- 2-Heptenoic acid
- 7-[[(2R)-2-amino-2-carboxyethyl]thio]-2-[[[(1S)-2,2-dimethylcyclopropyl]carbonyl]amino]-
- ammonium salt (1:1)
- (2Z)-
- 2-Heptenoic acid
- 7-[[(2R)-2-amino-2-carboxyethyl]thio]-2-[[[(1S)-2,2-dimethylcyclopropyl]carbonyl]amino]-
- monoammoniu
CAS:
Description:
Applications Sodium salt of Cilastatin (C441100), which prevents renal metabolism of penem and carbapenem antibiotics by specific and reversible dehydropeptidase I inhibition. Antibacterial adjunct.
References Finlay, K.R., et al.: Invest. Ophthalmol. Visual Sci., 24, 1147 (1983); Norrby, S.R., et al.: Antimicrob. Agents Chemother., 23, 300 (1983); Washburn, D.E., et al.: J. Antimicrob. Chemother., 12, 39 (1983);
Notice:
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Brand:
TRC
Long term storage:
Notes:
Chemical properties
Molecular weight:
375.484
Formula:
C16H26N2O5S•(HN)
Color/Form:
Neat
InChI:
1H3/b12-6-, /t10-,11+, /m1./s1, InChI=1S/C16H26N2O5S.H3N/c1-16(2)8-10(16)13(19)18-12(15(22)23)6-4-3-5-7-24-9-11(17)14(20)21, /h6,10-11H,3-5,7-9,17H2,1-2H3,(H,18,19)(H,20,21)(H,22,23)
InChI key:
InChIKey=PEHMSHKUJVYVPY-QBNHLFMHSA-N
SMILES:
CC1(C)C[C@@H]1C(=O)N/C(=C\CCCCSC[C@H](N)C(=O)O)C(=O)O.N
MDL:
Melting point:
Boiling point:
Flash point:
Density:
Concentration:
EINECS:
Merck:
HS code:
Technical inquiry about: TR-C441110 Cilastatin Ammonium Salt
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