Cilazaprilat-d5

CAS: 90139-06-3

Ref. TR-C441212

Product Information

• Name: Cilazaprilat-d5
• Synonyms: (4S,7S)-7-[[(1S)-1-carboxy-3-(2,3,4,5,6-pentadeuteriophenyl)propyl]amino]-6-oxo-1,2,3,4,7,8,9,10-octahydropyridazino[1,2-a]diazepine-4-carboxylic acid, (1S,9S)-9-[[(1S)-1-Carboxy-3-phenylpropyl]amino]octahydro-10-oxo-6H-pyridazino[1,2-a][1,2]diazepine-1-carboxylic acid, (1S,9S)-9-{[(1S)-1-Carboxy-3-phenylpropyl]amino}-10-oxooctahydro-6H-pyridazino[1,2-a][1,2]diazepine-1-carboxylic acid, 6H-Pyridazino[1,2-a][1,2]diazepine-1-carboxylic acid, 9-[(1-carboxy-3-phenylpropyl)amino]octahydro-10-oxo-, [1S-[1α,9α(R*)]]-, 6H-pyridazino[1,2-a][1,2]diazepine-1-carboxylic acid, 9-[[(1S)-1-carboxy-3-phenylpropyl]amino]octahydro-10-oxo-, (1S,9S)-, 90139-06-3, Ro 31-3113, Cilazaprilat

Description

Applications Isotope labelled analogue of Cilazaprilat (C441210), the active metabolite of Cilazapril (C441200). Cilazaprilat is an ACE inhibitor and antihypertensive agent.
References Natoff, I.L., et al.: J. Cardiovasc. Pharmacol., 7, 569 (1985), Szucs, T., et al.: Drugs, 41, Suppl.1, 18 (1991), Pordy, R.C., et al.: Cardiology, 86, 41 (1995),

• Brand: TRC

Chemical properties

• Molecular weight: 394.476
• Formula: C₂₀D₅H₂₂N₃O₅
• Color/Form: Neat
• InChI: InChI=1S/C20H27N3O5/c24-18-15(8-4-12-22-13-5-9-17(20(27)28)23(18)22)21-16(19(25)26)11-10-14-6-2-1-3-7-14/h1-3,6-7,15-17,21H,4-5,8-13H2,(H,25,26)(H,27,28)/t15-,16-,17-/m0/s1/i1D,2D,3D,6D,7D
• InChI key: InChIKey=UVAUYSRYXACKSC-KLPAFQCTSA-N
• SMILES: [2H]c1c([2H])c([2H])c(CC[C@H](N[C@H]2CCCN3CCC[C@@H](C(=O)O)N3C2=O)C(=O)O)c([2H])c1[2H]