Cilofungin

CAS: 79404-91-4

Ref. TR-C441400

Product Information

• Name: Cilofungin
• Synonyms: 1-[(4R,5R)-4,5-Dihydroxy-N2-[4-(octyloxy)benzoyl]-L-ornithine]-echinocandin B, 1H-Dipyrrolo[2,1-c:2',1'-l][1,4,7,10,13,16]hexaazacycloheneicosine Cyclic Peptide derivative, Antibiotic LY 121019, L 646991,(2alpha,3beta,4beta)-(4R,5R)-4,5-Dihydroxy-N2-[4-(octyloxy)benzoyl]-L-ornithyl-L-threonyl-trans-4-hydroxy-L-prolyl-(S)-4-hydroxy-4-(4-hydroxyphenyl)-L-threonyl-L-threonyl-3-hydroxy-4-methyl-L-proline Cyclic (6-1)-peptide, LY 121019, Cilofungin [USAN:INN], (4R,5R)-4,5-Dihydroxy-N(sup 2)-(p-(octyloxy)benzoyl)-L-ornithyl-L-threonyl-trans-4-hydroxy-L-prolyl-(S)-4-hydroxy-4-(p-hydroxyphenyl)-L-threonyl-L-threonyl-(3S,4S)-3-hydroxy-4-methyl-L-proline cyclic (6-1)-peptide, 1-((4R,5R)-4,5-Dihydroxy-N(sup 2)-(p-(octyloxy)benzoyl)-L-ornithine)echinocandin B, Cilofungina, Cilofungina [INN-Spanish], Cilofunginum, Cilofunginum [INN-Latin], Echinocandin B, 1-((4R,5R)-4,5-dihydroxy-N(sup 2)-(4-(octyloxy)benzoyl)-L-ornithine)-, Ly 121019, Unii-8Zjc54A39X, Echinocandin B, 1-((4R,5R)-4,5-dihydroxy-N2-(4-(octyloxy)benzoyl)-L-ornithine)-, N-[(2R,11R,12R,15S,16S)-23-[(1S,2S)-1,2-dihydroxy-2-(4-hydroxyphenyl)ethyl]-2,11,12,15-tetrahydroxy-6,20-bis(1-hydroxyethyl)-16-methyl-5,8,14,19,22,25-hexaoxotetracosahydro-1H-dipyrrolo[2,1-c:2',1'-l][1,4,7,10,13,16]hexaazacyclohenicosin-9-yl]-4-(octyloxy)benzamide

Description

Applications Cilofungin is a lipopeptide from echinocandin class of antifungal drugs which inhibits the synthesis of glucan in the fungal cell walls.
References Denning D.: Lancet, 362, 1142 (2003);

• Brand: TRC

Chemical properties

• Molecular weight: 1030.12
• Formula: C₄₉H₇₁N₇O₁₇
• Color/Form: Neat
• InChI: InChI=1S/C49H71N7O17/c1-5-6-7-8-9-10-19-73-31-17-13-28(14-18-31)42(65)50-32-21-34(61)45(68)54-47(70)38-39(62)24(2)22-56(38)49(72)36(26(4)58)52-46(69)37(41(64)40(63)27-11-15-29(59)16-12-27)53-44(67)33-20-30(60)23-55(33)48(71)35(25(3)57)51-43(32)66/h11-18,24-26,30,32-41,45,57-64,68H,5-10,19-23H2,1-4H3,(H,50,65)(H,51,66)(H,52,69)(H,53,67)(H,54,70)
• InChI key: InChIKey=ZKZKCEAHVFVZDJ-UHFFFAOYSA-N
• SMILES: CCCCCCCCOc1ccc(C(=O)NC2CC(O)C(O)NC(=O)C3C(O)C(C)CN3C(=O)C(C(C)O)NC(=O)C(C(O)C(O)c3ccc(O)cc3)NC(=O)C3CC(O)CN3C(=O)C(C(C)O)NC2=O)cc1