Cinobufotalin

CAS: 1108-68-5

Ref. TR-C475503

Product Information

• Name: Cinobufotalin
• Synonyms: (3ß,5ß,15ß,16ß)-16-(acetyloxy)-14,15-epoxy-3,5-dihydroxy-bufa-20,22-dienolide, (3Beta,5Beta,15Beta,16Beta)-16-(Acetyloxy)-3,5-Dihydroxy-14,15-Epoxybufa-20,22-Dienolide, (3β,5β,15β,16β)-16-(Acetyloxy)-14,15-epoxy-3,5-dihydroxybufa-20,22-dienolide, 14,15-Epoxy-14H-cyclopenta[a]phenanthrene, bufa-20,22-dienolide deriv., 5-beta-Bufa-20,22-dienolide, 14,15-beta-epoxy-3-beta,5,16-beta-trihydroxy-, 16-acetate, 5beta-Bufa-20,22-dienolide, 14,15beta-epoxy-3beta,5,16beta-trihydroxy-, 16-acetate, 5β-Bufa-20,22-dienolide, 14,15β-epoxy-3β,5,16β-trihydroxy-, 16-acetate, Bufa-20,22-dienolide, 16-(acetyloxy)-14,15-epoxy-3,5-dihydroxy-, (3beta,5beta,15beta,16beta)-, Bufa-20,22-dienolide, 16-(acetyloxy)-14,15-epoxy-3,5-dihydroxy-, (3β,5β,15β,16β)-, Cinobufotlin, Nsc 90326

Description

Applications Cinobufotalin is used in combination with irinotecan and capecitabine for treating advanced colorectal cancer, study of the clinical curative effect in the treatment of cancer pain, pre-clinical evaluation of cinobufotalin as potential anti-lung cancer agent.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Qian, M., et al.: Chongqing Yixue, 44, 3112 (2015); Yu, B., et al.: Xiandai Zhongxiyi Jiehe Zazhi, 24, 3997 (2015); Kai, S., et al.: Biochem. Biophys. Res. Commun., 452, 768 (2014)

• Brand: TRC

Chemical properties

• Molecular weight: 458.54
• Formula: C₂₆H₃₄O₇
• Color/Form: Neat
• InChI: InChI=1S/C26H34O7/c1-14(27)32-21-20(15-4-5-19(29)31-13-15)24(3)10-7-17-18(26(24)22(21)33-26)8-11-25(30)12-16(28)6-9-23(17,25)2/h4-5,13,16-18,20-22,28,30H,6-12H2,1-3H3/t16-,17-,18+,20-,21+,22+,23+,24+,25-,26+/m0/s1
• InChI key: InChIKey=KBKUJJFDSHBPPA-KDZUSLARSA-N
• SMILES: CC(=O)O[C@@H]1C(c2ccc(=O)oc2)[C@@]2(C)CC[C@H]3[C@@H](CC[C@]4(O)C[C@@H](O)CC[C@]34C)[C@]23O[C@H]13