Clemastine Fumarate

CAS: 14976-57-9

Ref. TR-C568500

Product Information

• Name: Clemastine Fumarate
• Synonyms: (2R)-2-[2-[(R)-1-(4-Chlorophenyl)-1-phenylethoxy]ethyl]-1-methylpyrrolidine (E)-butenedioate, Pyrrolidine, 2-[2-[(1R)-1-(4-chlorophenyl)-1-phenylethoxy]ethyl]-1-methyl-, (2R)-, (2E)-2-butenedioate (1:1), Pyrrolidine, 2-[2-[1-(4-chlorophenyl)-1-phenylethoxy]ethyl]-1-methyl-, [R-(R*,R*)]-, (E)-2-butenedioate (1:1), Agasten, Aloginan, Alphamin, Anhistan, Bravegyl, Clemastine hydrogen fumarate, Fuluminol, HS 592, Inbestan, Kinotomin, Lacretin, Lecasol, Maikohis, Mallermin F, Marsthine, Masletine, Meclastine fumarate, Mecloprodine, Piloral, Reconin, Tavegil, Tavegyl, Tavist, Telgin, Telgin G, Trabest, Xolamin, Pyrrolidine, 2-[2-[(p-chloro-alpha-methyl-alpha-phenylbenzyl)oxy]ethyl]-1-methyl-, (+)-, fumarate (1:1) (8CI), (+)-2-[2-[(p-Chloro-alpha-methyl-alpha-phenylbenzyl)oxy]ethyl]-1-methylpyrrolidine fumarate, (+)-(2R)-2-[2-[[(R)-p-Chloro-alpha-methyl-alpha-phenylbenzyl]oxy]ethyl]-1-methylpyrrolidine, (+)-2-[2-[(p-Chloro-α-methyl-α-phenylbenzyl)oxy]ethyl]-1-methylpyrrolidine fumarate, (2R)-2-[2-[(1R)-1-(4-Chlorophenylethoxy)]Ethyl]-1-Methyl-2-Pyrrolidine Fumarate, (2R)-2-{2-[(1R)-1-(4-chlorophenyl)-1-phenylethoxy]ethyl}-1-methylpyrrolidine, (2R)-2-{2-[(1R)-1-(4-chlorophenyl)-1-phenylethoxy]ethyl}-1-methylpyrrolidine (2E)-but-2-enedioate, 2-{2-[1-(4-Chlorophenyl)-1-Phenylethoxy]Ethyl}-1-Methylpyrrolidine, Clemastine, Clemastine Fumarate Salt, Clemastine Hydrogen Fumarate, Clemastinum, Hs 592, Pyrrolidine, 2-2-(1R)-1-(4-chlorophenyl)-1-phenylethoxyethyl-1-methyl-, (2R)-, Pyrrolidine, 2-[2-[(1R)-1-(4-chlorophenyl)-1-phenylethoxy]ethyl]-1-methyl-, (2R)-, (2E)-2-butenedioate (1:1), Pyrrolidine, 2-[2-[(p-chloro-α-methyl-α-phenylbenzyl)oxy]ethyl]-1-methyl-, (+)- (8CI), Pyrrolidine, 2-[2-[(p-chloro-α-methyl-α-phenylbenzyl)oxy]ethyl]-1-methyl-, (+)-, fumarate (1:1), Pyrrolidine, 2-[2-[1-(4-chlorophenyl)-1-phenylethoxy]ethyl]-1-methyl-, [R-(R*,R*)]-, Pyrrolidine, 2-[2-[1-(4-chlorophenyl)-1-phenylethoxy]ethyl]-1-methyl-, [R-(R*,R*)]-, (E)-2-butenedioate (1:1)

Description

Applications H1 Histamine receptor antagonist. Antihistaminic.
References Weidmann, et al.: Boll. Chim. Farm., 106, 467 (1967), Gober, B., et al.: Pharmazie, 43, 539 (1988), Breccia, A., et al.: Curr. Ther. Res., 49, 622 (1991), Schran, H., et al.: J. Clin. Pharmacol., 36, 911 (1996),

• Brand: TRC

Chemical properties

• Molecular weight: 459.96
• Formula: C₂₁H₂₆ClNO·C₄H₄O₄
• Color/Form: White
• InChI: 2-1+/t20-,21-, 1-2H,(H,5,6)(H,7,8)/b, 5-3(6)1-2-4(7)8/h3-5,7-8,10-13,20H,6,9,14-16H2,1-2H3, /m1./s1, InChI=1S/C21H26ClNO.C4H4O4/c1-21(17-7-4-3-5-8-17,18-10-12-19(22)13-11-18)24-16-14-20-9-6-15-23(20)2
• InChI key: InChIKey=PMGQWSIVQFOFOQ-YKVZVUFRSA-N
• SMILES: CN1CCC[C@@H]1CCO[C@](C)(c1ccccc1)c1ccc(Cl)cc1.O=C(O)/C=C/C(=O)O