Clobetasone 17-Propionate

CAS: 25122-56-9

Ref. TR-C583535

Product Information

• Name: Clobetasone 17-Propionate
• Synonyms: (16ß)-21-Chloro-9-fluoro-16-methyl-3,11,20-trioxopregna-1,4-dien-17-yl Propionate, (16ß)-21-Chloro-9-fluoro-16-methyl-17-(1-oxopropoxy)pregna-1,4-diene-3,11,20-trione, 21-Chloro-9-fluoro-17-hydroxy-16ß-methylpregna-1,4-diene-3,11,20-trione propionate, Clobetasone propionate, Clobetasone-17-propionate, Pregna-1,4-diene-3,11,20-trione, 21-chloro-9-fluoro-16-methyl-17-(1-oxopropoxy)-, (16β)-, (16β)-21-Chloro-9-fluoro-16-methyl-17-(1-oxopropoxy)pregna-1,4-diene-3,11,20-trione, Pregna-1,4-diene-3,11,20-trione, 21-chloro-9-fluoro-17-hydroxy-16β-methyl-, propionate

Description

Impurity Clobetasone Butyrate EP Impurity H
Applications Clobetasone-17-propionate is derived from Clobetasol (Clobetasol Propionate EP Impurity G) (C583490), which is a topical corticosteroid. Glucocorticoid; anti-inflammatory.
References Olsen, E.A., et al.: J. Am. Acad. Dermatol., 15, 246 (1986)

• Brand: TRC

Chemical properties

• Molecular weight: 464.95
• Formula: C₂₅H₃₀ClFO₅
• Color/Form: Neat
• InChI: InChI=1S/C25H30ClFO5/c1-5-21(31)32-25(20(30)13-26)14(2)10-18-17-7-6-15-11-16(28)8-9-22(15,3)24(17,27)19(29)12-23(18,25)4/h8-9,11,14,17-18H,5-7,10,12-13H2,1-4H3/t14-,17-,18-,22-,23-,24-,25-/m0/s1
• InChI key: InChIKey=VAUBWHIQMRKGBN-BHHHYXKXSA-N
• SMILES: CCC(=O)O[C@]1(C(=O)CCl)[C@@H](C)C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(F)C(=O)C[C@@]21C