Clocortolone-d3

CAS: 4828-27-7

Ref. TR-C583802

Product Information

• Name: Clocortolone-d3
• Synonyms: (6S,8S,9R,10S,11S,13S,14S,16R,17S)-9-chloro-6-fluoro-11-hydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-16-(trideuteriomethyl)-7,8,11,12,14,15,16,17-octahydro-6H-cyclopenta[a]phenanthren-3-one, (6Alpha,11Beta,16Alpha)-9-Chloro-6-Fluoro-11,21-Dihydroxy-16-Methylpregna-1,4-Diene-3,20-Dione, (6Alpha,8Xi,10Xi,13Xi,14Xi,16Alpha,17Xi)-9-Chloro-6-Fluoro-11,21-Dihydroxy-16-Methylpregna-1,4-Diene-3,20-Dione, (6α,11β,16α)-9-Chloro-6-fluoro-11,21-dihydroxy-16-methylpregna-1,4-diene-3,20-dione, 9-Alpha-Chloro-6-Alpha-Fluoro-11-Beta,21-Dihydroxy-16-Alpha-Methylpregna-1,4-Diene-3,20-Dione, 9-Chloro-6α-fluoro-11β,21-dihydroxy-16α-methylpregna-1,4-diene-3,20-dione, 9-Chloro-6α-fluoro-11β,21-dihydroxy-17α-methylpregna-1,4-diene-3,20-dione, 9-Chloro-6α-fluoro-16α-methyl-1,4-pregnadiene-11β,21-diol-3,20-dione, Clorcortelone, Pregna-1,4-diene-3,20-dione, 9-chloro-6-fluoro-11,21-dihydroxy-16-methyl-, (6α,11β,16α)-, Pregna-1,4-diene-3,20-dione, 9-chloro-6α-fluoro-11β,21-dihydroxy-16α-methyl-

Description

Applications Isotope labelled Corticosteroid (C583800) is used in the treatment of skin inflammation and other skin conditions arising for dermatoses.
References Rehm, K. et al.: Pharmaz. Zeit., 127, 888 (1982);

• Brand: TRC

Chemical properties

• Molecular weight: 413.925
• Formula: C₂₂D₃H₂₅ClFO₄
• Color/Form: Neat
• InChI: InChI=1S/C22H28ClFO4/c1-11-6-13-14-8-16(24)15-7-12(26)4-5-21(15,3)22(14,23)18(28)9-20(13,2)19(11)17(27)10-25/h4-5,7,11,13-14,16,18-19,25,28H,6,8-10H2,1-3H3/t11-,13+,14+,16+,18+,19-,20+,21+,22+/m1/s1/i1D3
• InChI key: InChIKey=YMTMADLUXIRMGX-OAXOUBHMSA-N
• SMILES: [2H]C([2H])([2H])[C@@H]1C[C@H]2[C@@H]3C[C@H](F)C4=CC(=O)C=C[C@]4(C)[C@@]3(Cl)[C@@H](O)C[C@]2(C)[C@H]1C(=O)CO