Cloprednol

CAS: 5251-34-3

Ref. TR-C587295

Product Information

• Name: Cloprednol
• Synonyms: (8S,9S,10R,11S,13S,14S,17R)-6-chloro-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-9,11,12,14,15,16-hexahydro-8H-cyclopenta[a]phenanthren-3-one, (11Beta)-6-Chloro-11,17,21-Trihydroxypregna-1,4,6-Triene-3,20-Dione, (11β)-6-Chloro-11,17,21-trihydroxypregna-1,4,6-triene-3,20-dione, (8Xi,10Xi,11Beta,13Xi)-6-Chloro-11,17,21-Trihydroxypregna-1,4,6-Triene-3,20-Dione, 6-Chloro-11beta,17,21-trihydroxypregna-1,4,6-triene-3,20-dione, 6-Chloro-11beta,17alpha, 21-trihydroxypregn-1,4,6-triene-3,20-dione, Cloprednol [USAN:INN:BAN], Cloprednole, Cloprednolum, Cloprednolum [INN-Latin], Cloradryn, Novacort, Pregna-1,4,6-triene-3,20-dione, 6-chloro-11,17,21-trihydroxy-, (11beta)-, Pregna-1,4,6-triene-3,20-dione, 6-chloro-11,17,21-trihydroxy-, (11β)-, Pregna-1,4,6-triene-3,20-dione, 6-chloro-11β,17,21-trihydroxy-, Rs 4691, Synestan, Syntestan, Unii-Syp56O3Gjg

Description

Applications A systematic corticosteroid. Anti-inflammatory.
References Mroszczak, E.J. et al.: J. Pharmac. Sci., 67, 920 (1978); Moellmann, H. et al.: Int. J. Clin. Pharmacol. Therap., 34, 1 (1996);

• Brand: TRC

Chemical properties

• Molecular weight: 392.87
• Formula: C₂₁H₂₅ClO₅
• Color/Form: Neat
• InChI: InChI=1S/C21H25ClO5/c1-19-5-3-11(24)7-14(19)15(22)8-12-13-4-6-21(27,17(26)10-23)20(13,2)9-16(25)18(12)19/h3,5,7-8,12-13,16,18,23,25,27H,4,6,9-10H2,1-2H3/t12-,13-,16-,18+,19-,20-,21-/m0/s1
• InChI key: InChIKey=YTJIBEDMAQUYSZ-FDNPDPBUSA-N
• SMILES: C[C@]12C[C@H](O)[C@H]3[C@@H](C=C(Cl)C4=CC(=O)C=C[C@@]43C)[C@@H]1CC[C@]2(O)C(=O)CO