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1-(3-Chloro-2-hydroxypropyl)-2-nitroimidazole
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1-(3-Chloro-2-hydroxypropyl)-2-nitroimidazole

CAS: 13551-86-5

Ref. TR-C592035

10g
1,060.00 €
Estimated delivery in United States, on Friday 27 Dec 2024

Product Information

Name:
1-(3-Chloro-2-hydroxypropyl)-2-nitroimidazole
Controlled Product
Synonyms:
  • 1-chloro-3-(2-nitroimidazol-1-yl)propan-2-ol
  • 1H-Imidazole-1-ethanol, α-(chloromethyl)-2-nitro-
  • α-(Chloromethyl)-2-nitro-1H-imidazole-1-ethanol
  • Ro 07-0269
  • Imidazole-1-ethanol, α-(chloromethyl)-2-nitro-
Description:

Applications 1-(3-Chloro-2-hydroxypropyl)-2-nitroimidazole is an intermediate in the synthesis of 1-(2,3-Epoxypropyl)-2-nitroimidazole (B592583) which is an intermediate in the synthesis of Pimonidazole-d10 (P447814). Isotope labelled Pimonidazole (P447813) is an effective and nontoxic hypoxia detection reagent. Pimonidazole forms adducts with thiol groups in proteins, peptides and amino acids. It abels hypoxic tumor cells in vivo. Also labels hypoxic mesenchymal stem cells in mouse bone marrow.
References Sato et al.: PLoS One 11 e0165946 PMID:(2016); Bennewith et al.: Cancer Res. 62 6827 PMID: 12460894, (2002)

Notice:
Our products are intended for lab use only. For any other use, please contact us.
Brand:
TRC
Long term storage:
Notes:

Chemical properties

Molecular weight:
205.599
Formula:
C6H8ClN3O3
Color/Form:
Neat
InChI:
InChI=1S/C6H8ClN3O3/c7-3-5(11)4-9-2-1-8-6(9)10(12)13/h1-2,5,11H,3-4H2
SMILES:
O=[N+]([O-])c1nccn1CC(O)CCl
MDL:
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Hazard Info

UN Number:
EQ:
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H Statements:
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Forbidden to fly:
Hazard Info:
Packing Group:
LQ:

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