Coelenterazine, native

CAS: 55779-48-1

Ref. TR-C636000

Product Information

• Name: Coelenterazine, native
• Synonyms: 8-benzyl-6-(4-hydroxyphenyl)-2-[(4-hydroxyphenyl)methyl]-7H-imidazo[1,2-a]pyrazin-3-one, 2-[(4-Hydroxyphenyl)Methyl]-6-(4-Hydroxyphenyl)-8-(Phenylmethyl)-Imdazo[1,2-A]Pyrazin-3-(7H)-One, 6-(4-Hydroxyphenyl)-2-[(4-hydroxyphenyl)methyl]-8-(phenylmethyl)imidazo[1,2-a]pyrazin-3(7H)-one, 8-Benzyl-2-(4-Hydroxybenzyl)-6-(4-Hydroxyphenyl)Imidazo[1,2-A]Pyrazin-3(7H)-One, Coelenterazin, Coelenterazine, Coelenterazine luciferin, Coelenterazine ntv, Imidazo[1,2-a]pyrazin-3(7H)-one, 6-(4-hydroxyphenyl)-2-[(4-hydroxyphenyl)methyl]-8-(phenylmethyl)-, Luciferin, Luciferin (Oplophorus), NanoFuel, Native coelenterazine, Preluciferin, Preluciferin (Watasenia), Watasenia preluciferin

Description

Applications Coelenterazine is a luminophore of the aequorin complex which is oxidized by oxygen to illuminate at 465nm when Ca2+ binds to the complex. Used to measure Ca2+ concentration in cells with high sensitivity an dlarge dynamic range.
References Fluck, R.A., et al.: J. Cell Biol., 115, 1259 (1991), Jones, K., et al.: Trends Biotechnol., 17, 477 (1999), Dubuisson, M.L., et al.: Biochem. Pharmacol., 60, 471 (2000)

• Brand: TRC

Chemical properties

• Molecular weight: 423.46
• Formula: C₂₆H₂₁N₃O₃
• Color/Form: Neat
• InChI: InChI=1S/C26H21N3O3/c30-20-10-6-18(7-11-20)15-23-26(32)29-16-24(19-8-12-21(31)13-9-19)27-22(25(29)28-23)14-17-4-2-1-3-5-17/h1-13,16,27,30-31H,14-15H2
• InChI key: InChIKey=YHIPILPTUVMWQT-UHFFFAOYSA-N
• SMILES: O=c1c(Cc2ccc(O)cc2)nc2c(Cc3ccccc3)[nH]c(-c3ccc(O)cc3)cn1-2