Convallatoxin

CAS: 508-75-8

Ref. TR-C685075

Product Information

• Name: Convallatoxin
• Synonyms: Card-20(22)-enolide, 3-[(6-deoxy-a-L-mannopyranosyl)oxy]-5,14-dihydroxy-19-oxo-, (3ß,5ß)-, Convallatoxin (6CI,7CI,8CI), (3ß,5ß)-3-[(6-Deoxy-a-L-mannopyranosyl)oxy]-5,14-dihydroxy-19-oxocard-20(22)-enolide, Convallaotoxin, Convallaton, Convallatoxine, Convallatoxoside, Convallotoxin, Corglycon, Corglycone, Corglykon, Korglykon, NSC 407808, Strophanthidin a-L-rhamnoside, (3beta,5beta)-3-[(6-deoxy-alpha-L-mannopyranosyl)oxy]-5,14-dihydroxy-19-oxocard-20(22)-enolide, (3beta,5beta,17xi)-3-[(6-deoxy-L-mannopyranosyl)oxy]-5,14-dihydroxy-19-oxocard-20(22)-enolide, (3beta,5beta,8xi,9xi)-3-[(6-deoxy-alpha-L-mannopyranosyl)oxy]-5,14-dihydroxy-19-oxocard-20(22)-enolide, (3β,5β)-3-[(6-Deoxy-α-<span class="text-smallcaps">L</span>-mannopyranosyl)oxy]-5,14-dihydroxy-19-oxocard-20(22)-enolide, 3-[(6-Deoxyhexopyranosyl)Oxy]-5,14-Dihydroxy-19-Oxocard-20(22)-Enolide, 3beta-((6-Deoxy-alpha-L-mannopyranosyl)oxy)-5,14-dihydroxy-19-oxo-5beta-card-20(22)-enolide, Card-20(22)-enolide, 3-((6-deoxy-alpha-L-mannopyranosyl)oxy)-5,14-dihydroxy-19-oxo-, (3beta,5beta)-, Card-20(22)-enolide, 3-((6-deoxy-alpha-L-mannopyranosyl)oxy)-5,14-dihydroxy-19-oxo-, (3beta,5beta)- (9CI), Card-20(22)-enolide, 3-[(6-deoxy-α-<span class="text-smallcaps">L</span>-mannopyranosyl)oxy]-5,14-dihydroxy-19-oxo-, (3β,5β)-, Hsdb 3475, Mannopyranoside, strophanthidin-3,6-deoxy-, alpha-L-, Nsc 407808, Rhamnoside, strophanthidin-3, alpha-L-, Strophanthidin alpha-L-rhamnoside, Strophanthidin α-<span class="text-smallcaps">L</span>-rhamnoside, Strophanthidin, 3-(6-deoxy-alpha-L-mannopyranoside)

Description

Applications Convallatoxin is a cardenolide that is used in the treatment of congestive heart failure. It may also be used in the treatment of tumor cells at nanomolar concentrations due to its anti-proliferative effects; in particular, human lung cancer. It is naturally found in the roots of Adonis Amurensis.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Schneider, N., et al.: Nat. Prod. Res., (2015); Yin, L., et al.: Zhong Cao Yao, 45, 3361 (2014);

• Brand: TRC

Chemical properties

• Molecular weight: 550.64
• Formula: C₂₉H₄₂O₁₀
• Color/Form: White To Off-White
• InChI: InChI=1S/C29H42O10/c1-15-22(32)23(33)24(34)25(38-15)39-17-3-8-27(14-30)19-4-7-26(2)18(16-11-21(31)37-13-16)6-10-29(26,36)20(19)5-9-28(27,35)12-17/h11,14-15,17-20,22-25,32-36H,3-10,12-13H2,1-2H3/t15-,17-,18+,19-,20+,22-,23+,24+,25-,26+,27-,28-,29-/m0/s1
• InChI key: InChIKey=HULMNSIAKWANQO-JPJIYMDLSA-N
• SMILES: C[C@@H]1O[C@@H](O[C@H]2CC[C@]3(C=O)C4CC[C@]5(C)C(C6=CC(=O)OC6)CC[C@]5(O)[C@@H]4CC[C@]3(O)C2)[C@H](O)[C@H](O)[C@H]1O