Coptisine Chloride

CAS: 6020-18-4

Ref. TR-C685500

Product Information

• Name: Coptisine Chloride
• Synonyms: 6,7-Dihydrobis[1,3]benzodioxolo[5,6-a:4',5'-g]quinolizinium Chloride, 7,8,13,13a-Tetradehydro-2,3:9,10-bis(methylenedioxy)berbinium Chloride, 6,7-Dihydrobis[1,3]benzodioxolo[5,6-a:4',5'-g]quinolizinium Chloride, 6,7-Dihydro[1,3]Dioxolo[4,5-G][1,3]Dioxolo[7,8]Isoquino[3,2-A]Isoquinolin-5-Ium, 6,7-Dihydro[1,3]Dioxolo[4,5-G][1,3]Dioxolo[7,8]Isoquino[3,2-A]Isoquinolin-5-Ium Chloride, 7,12b-dihydro-6H-[1,3]dioxolo[4,5-g][1,3]dioxolo[7,8]isoquino[3,2-a]isoquinoline, 7,8,13,13a-Tetradehydro-2,3:9,10-bis(methylenedioxy)berbinium chloride, Berbinium, 7,8,13,13a-tetradehydro-2,3:9,10-bis(methylenedioxy)-, chloride, Bis[1,3]benzodioxolo[5,6-a:4′,5′-g]quinolizinium, 6,7-dihydro-, chloride, Bis[1,3]benzodioxolo[5,6-a:4′,5′-g]quinolizinium, 6,7-dihydro-, chloride (1:1), Coptisine hydrochloride, Coptisine chloride

Description

Stability Hygroscopic
Applications Coptisine is an alkaloid found in Chinese goldthread (Coptis chinensis). A bacterial collagenase inhibitor. Coptisine has been found to reversibly inhibit Monoamine oxidase A in mice, pointing to a potential role as a natural antidepressant.
References Blaney, W., et al.: Physiol. Entomol., 12, 281 (1987), Sethi, M., et al.: J. Pharm. Sci., 72, 538 (1983), Yahara, S., et al.: Chem. Pharm. Bull., 33, 527 (1985),

• Brand: TRC

Chemical properties

• Molecular weight: 355.77
• Formula: C₁₉H₁₄NO₄·Cl
• Color/Form: Neat
• InChI: /h1-2,5-8H,3-4,9-10H2, /p-1, 1H/q+1, InChI=1S/C19H14NO4.ClH/c1-2-16-19(24-10-21-16)14-8-20-4-3-12-6-17-18(23-9-22-17)7-13(12)15(20)5-11(1)14
• SMILES: [Cl-].c1c2c(cc3c1OCO3)-c1cc3ccc4c(c3c[n+]1CC2)OCO4