Product Information
Name:β-Cortolone
Controlled Product
Synonyms:
- 3α,17,20β,21-Tetrahydroxy-11-pregnanone
- 5β-Pregnan-11-one
- 3α,17,20β,21-tetrahydroxy- (7CI,8CI)
- 20β-Cortolone
- 20β-Hexahydrocortisone
- 3α,17,20β,21-Tetrahydroxy-5β-pregnan-11-one
- 3α,17α,20β,21-Tetrahydroxy-5β-pregnan-11-one
- 5β-Pregnan-3α,17α,20β,21-tetrol-11-one
- 5β-Pregnane-3α,17α,20β,21-tetrol-11-one
- NSC 56997
Brand:TRC
Description:Applications β-Cortolone is a metabolite of Cortisol (H714615), a steroid hormone, more specifically a glucocorticoid, produced by the zona fasciculata of the adrenal gland. Cortisol is released in response to stress and a low level of blood glucocorticoids. Its primary functions are to increase blood sugar through gluconeogenesis; suppress the immune system; and aid in fat, protein and carbohydrate metabolism.References Fukushima, D.K., et. al.: Steroids, 35, 209 (1980); Vigore, L., et al.: Cancer Ther., 6, 699 (2008); Puurunen, J., et al.: J. Clin. Endocrinol. Metab., 94, 1973 (2009); Lemos, D., et al.: J. Endocrinol., 201, 275 (2009); Chen, S., et al.: Am. J. Physiol., 296 (2009)
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:366.49
Formula:C21H34O5
Color/Form:Off-White
InChI:InChI=1S/C21H34O5/c1-19-7-5-13(23)9-12(19)3-4-14-15-6-8-21(26,17(25)11-22)20(15,2)10-16(24)18(14)19/h12-15,17-18,22-23,25-26H,3-11H2,1-2H3/t12-,13-,14+,15+,17-,18-,19+,20+,21+/m1/s1
InChI key:InChIKey=JXCOSKURGJMQSG-AIEJOZITSA-N
SMILES:C[C@]12CC[C@@H](O)C[C@H]1CC[C@@H]1[C@@H]2C(=O)C[C@@]2(C)[C@H]1CC[C@]2(O)[C@H](O)CO
Technical inquiry about: β-Cortolone
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