Cortisol-9,11,12,12-d4

CAS: 73565-87-4

Ref. TR-C696302

Product Information

• Name: Cortisol-9,11,12,12-d4
• Synonyms: Hydrocortisone-9a,11a,12a,12ß-D4

Description

Applications Labelled Cortisol (H714615). Cortisol, or Hydrocortisone, is a steroid hormone, more specifically a glucocorticoid, produced by the zona fasciculata of the adrenal gland. Cortisol is released in response to stress and a low level of blood glucocorticoids. Its primary functions are to increase blood sugar through gluconeogenesis; suppress the immune system; and aid in fat, protein and carbohydrate metabolism.
References Hechter, O., et al.: Arch. Biochem. Biophys., 25, 457 (1950), Colingsworth, D.R., et al.: J. Biol. Chem., 203, 807 (1953), Florey, K., et al.: Anal. Profiles Drug Subs., 12, 277 (1983),

• Brand: TRC

Chemical properties

• Molecular weight: 366.48
• Formula: C₂₁H₄H₂₆O₅
• Color/Form: Off-White
• InChI: InChI=1S/C21H30O5/c1-19-7-5-13(23)9-12(19)3-4-14-15-6-8-21(26,17(25)11-22)20(15,2)10-16(24)18(14)19/h9,14-16,18,22,24,26H,3-8,10-11H2,1-2H3/t14-,15-,16-,18+,19-,20-,21-/m0/s1/i10D2,16D,18D
• InChI key: InChIKey=JYGXADMDTFJGBT-SJFQKQTESA-N
• SMILES: [2H]C1([2H])[C@]([2H])(O)[C@@]2([2H])[C@@H](CCC3=CC(=O)CC[C@@]32C)[C@@H]2CC[C@@](O)(C(=O)CO)[C@]21C