((1-Chloro-2-methylpropan-2-yl)oxy)trimethylsilane
CAS:
Ref. TR-C897545
1g
437.00€
500mg
243.00€
2500mg
969.00€
Product Information
Name:((1-Chloro-2-methylpropan-2-yl)oxy)trimethylsilane
Controlled Product
Brand:TRC
Description:Applications ((1-Chloro-2-methylpropan-2-yl)oxy)trimethylsilane is an intermediate for the synthesis of 3-Hydroxy Bortezomib (H818150), which is a metabolite of Bortezomib (B675700); the first proteasome inhibitor to be approved by the US FDA for multiple myeloma, a blood cancer.References Nawrocki, S.T., et al.: Cancer Res., 65, 11510 (2005); Drahl, C.: Chem. and Eng. News, 87, 41 (2009)
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Chemical properties
Molecular weight:180.75
Formula:C7H17ClOSi
Color/Form:Neat
InChI:InChI=1S/C7H17ClOSi/c1-7(2,6-8)9-10(3,4)5/h6H2,1-5H3
InChI key:InChIKey=XAQMYGFHWPXCEG-UHFFFAOYSA-N
SMILES:CC(C)(CCl)O[Si](C)(C)C
Technical inquiry about: ((1-Chloro-2-methylpropan-2-yl)oxy)trimethylsilane
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