N-[(2'-Cyano[1,1'-biphenyl]-4-yl)methyl]-L-valine Methyl Ester Hydrochloride

CAS: 482577-59-3

Ref. TR-C962340

Product Information

• Name: N-[(2'-Cyano[1,1'-biphenyl]-4-yl)methyl]-L-valine Methyl Ester Hydrochloride
• Synonyms: L-Valine, N-[(2'-cyano[1,1'-biphenyl]-4-yl)methyl]-, methyl ester, hydrochloride (1:1), : L-Valine, N-[(2'-cyano[1,1'-biphenyl]-4-yl)methyl]-, methyl ester, monohydrochloride (9CI), N-[(2'-Cyano[1,1'-biphenyl]-4-yl)methyl]-L-valine methyl ester hydrochloride (1:1)
• Brand: TRC

Description

Applications Hydrochloride Salt of N-[(2'-Cyano[1,1'-biphenyl]-4-yl)methyl]-L-valine Methyl Ester is an intermediate in the preparation of angiotensin II type 1 receptor antagonists.
References Goossen, L.J. et al.: J. Org. Chem., 72, 7473 (2007); Nie, Y. et al.: Bioorg. Med. Chem., 20, 2747 (2012);

Chemical properties

• Molecular weight: 358.86
• Formula: C₂₀H₂₂N₂O₂·ClH
• Color/Form: Neat
• InChI: InChI=1S/C20H22N2O2.ClH/c1-14(2)19(20(23)24-3)22-13-15-8-10-16(11-9-15)18-7-5-4-6-17(18)12-21;/h4-11,14,19,22H,13H2,1-3H3;1H/t19-;/m0./s1
• InChI key: InChIKey=GMQNSDJQDGPMQI-IBGZPJMESA-N
• SMILES: COC(=O)[C@@H](NCc1ccc(-c2ccccc2C#N)cc1)C(C)C.Cl