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6-Cyano-7-nitroquinoxaline-2,3-dione

CAS:

Ref. TR-C982000

5mg
93.00€
25mg
210.00€
50mg
345.00€
6-Cyano-7-nitroquinoxaline-2,3-dione
TRC

Product Information

Name:6-Cyano-7-nitroquinoxaline-2,3-dione
Controlled Product
Synonyms:
  • 7-nitro-2,3-dioxo-1,4-dihydroquinoxaline-6-carbonitrile
Brand:TRC
Description:

Stability Store Tightly Sealed at RT
Applications A potent, competitive kainate/quisqualate (non-NMDA) receptor antagonist. IC50 of tritiated ligands to rat cortical membranes by CNQX: AMPA, Kainate and CPP are 0.3mM, 1.5mM, and 25mM, respectively.
References Honore, et al. Science, 241, 701 (1988),Haas, H.S., et al.: Int. J. Oncol., 27, 867 (2005), Kobayashi, K., et al.: J. Pharmacol. Sci., 108, 517 (2008), Shabat-Simon, M., et al.: J. Neurosci., 28, 8406 (2008), Cruz, L.A., et al.: J. Med. Chem., 51, 5856 (2008),

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Chemical properties

Molecular weight:232.15
Formula:C9H4N4O4
Color/Form:Neat
InChI:InChI=1S/C9H4N4O4/c10-3-4-1-5-6(2-7(4)13(16)17)12-9(15)8(14)11-5/h1-2H,(H,11,14)(H,12,15)
SMILES:N#Cc1cc2[nH]c(=O)c(=O)[nH]c2cc1[N+](=O)[O-]

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