Product Information
- 4-Pyridinecarbonitrile
- Isonicotinonitrile (6CI,8CI)
- 4-Azabenzonitrile
- 4-Pyridinenitrile
- 4-Pyridyl cyanide
- 4-Pyridylcarbonitrile
- Isonicotinic acid nitrile
- NSC 60681
- gamma-Cyanopyridine
- Fampridine Impurity 2
- See more synonyms
- Ethionamide Impurity B
- Isoniazid Impurity C
- 4-Nitrilopyridine
- 4-cyano Pyridine
- Isonicotinonitril
- Isonicotinonitrile
- Isonicotinonitrilo
- Nsc 60681
- Pyridine, 4-Cyano-
- Pyridine-3-Carbonitrile
- Pyridine-4-carbonitrile
- γ-Cyanopyridine
Applications 4-Cyanopyridine is a reagent for the synthesis of 1-tolyl-5-benzylthiotetrazole and 2-hexylthio-4-pyridinecarbonitrile, an antituberculotics. Preparation of the antihypertensive agent Pinacidil using the chemoselective and green oxidative rearrangement of an amidine and addition of an amine to a guanidine as the key step. Structure-based discovery of human L-xylulose reductase inhibitors from database screening and molecular docking. Human L-xylulose reductase (XR) is an enzyme of the glucuronic acid/uronate cycle of glucose metabolism with the possible target for treatment of the long-term complications of diabetes.
References Waisser, K., et al.: Folia Pharmaceutica Universitatis Carolinae, 18, 31 (1995); Carbone, V., et al.: Bioorg. Med. Chem., 13, 301 (2004); Baeten, M., et al.: Adv. Synth. Catal., 358, 826 (2016)
Chemical properties
Technical inquiry about: TR-C982225 4-Cyanopyridine
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