Cyclizine Lactate

CAS: 5897-19-8

Ref. TR-C987440

Product Information

• Name: Cyclizine Lactate
• Synonyms: 2-Hydroxy-propanoic acid compd. with 1-(diphenylmethyl)-4-methylpiperazine, Lactic acid, compd. with 1-(diphenylmethyl)-4-methylpiperazine, Lactic acid, salt with 1-diphenylmethyl-4-methylpiperazine, 1-(Diphenylmethyl)-4-methyl-piperazine mono(2-hydroxypropanoate), 1-(Diphenylmethyl)-4-methyl-piperazine monolactate, Valoid, 1-(Diphenylmethyl)-4-methylpiperazine monolactate, 1-Benzhydryl-4-methylpiperazine 2-hydroxypropanoate, 2-Hydroxypropanoic Acid - 1-(Diphenylmethyl)-4-Methylpiperazine (1:1), Bw 4783, Cyclizine lactate [USAN:BAN], Lactic acid, compd. with 1-(diphenylmethyl)-4-methylpiperazine (1:1), Lactic acid, salt with 1-diphenylmethyl-4-methylpiperazine, Piperazine, 1-(diphenylmethyl)-4-methyl-, mono(2-hydroxypropanoate), Piperazine, 1-(diphenylmethyl)-4-methyl-, monolactate, Propanoic acid, 2-hydroxy-, compd. with 1-(diphenylmethyl)-4-methylpiperazine (1:1), Unii-861R00J986

Description

Applications Cyclizine Lactate is a lactate salt of Cyclizine (C987805, HCl salt) which is a piperazine derivative with anti-emetic activity that is useful in the prevention and treatment of nausea and vomiting associated with motion sickness.
References Kuntzman, R., et al.: J. Pharmacol. Exp. Ther., 158, 332 (1967), Walker, R., et al.: Eur. J. Pharm. Sci., 4, 301 (1996), Dumasia, M., et al.: Xenobiotica, 32, 795 (2002)

• Brand: TRC

Chemical properties

• Molecular weight: 356.46
• Formula: C₂₁H₂₈N₂O₃
• Color/Form: Neat
• InChI: InChI=1S/C18H22N2.C3H3O3/c1-19-12-14-20(15-13-19)18(16-8-4-2-5-9-16)17-10-6-3-7-11-17;1-2(4)3(5)6/h2-11,18H,12-15H2,1H3;2,4H,(H,5,6)
• InChI key: InChIKey=LADXAFXKKFTLBT-UHFFFAOYSA-N
• SMILES: CN1CCN(C(c2ccccc2)c2ccccc2)CC1.[C]C(O)C(=O)O